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Fig. 7 | BMC Genomics

Fig. 7

From: 2.7 million samples genotyped for HLA by next generation sequencing: lessons learned

Fig. 7

Correlation between initial DNA concentration and read coverage per sample before (left panel) and after (right panel) August 2014. In August 2014 a new post-PCR equilibration strategy was introduced based on a Michaelis-Menten saturation curve (dashed line, left panel) estimated from the data. Solid lines show generalised additive model fits using a cubic penalised regression spline. The shaded bands around the regression lines indicate the pointwise 95% confidence intervals on the fitted values

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