Skip to main content

Table 1 NGS genotyping resolution for six HLA loci in 2.7 million DKMS donors

From: 2.7 million samples genotyped for HLA by next generation sequencing: lessons learned

  

Resolution

Locus

Number of samples

High [%]a

Intermediate [%]

Low [%]

HLA-A

2,710,959

99.60

0.40

0

HLA-B

2,708,617

98.13

1.87

0.001

HLA-C

2,706,849

96.78

3.22

0

HLA-DRB1

2,710,549

99.92

0.08

0

HLA-DQB1

2,710,553

98.82

1.18

0

HLA-DPB1

2,706,356

99.97

0.03

0

  1. anull alleles caused by a mutation outside of exons 2 and 3 remain unidentified