From: 2.7 million samples genotyped for HLA by next generation sequencing: lessons learned
Locus | Samples | Total novel alleles | Distinct novel alleles | Estimates of number of distinct novel alleles at n typed samples | ||
---|---|---|---|---|---|---|
3 M | 6 M | 9 M | ||||
HLA-A | 1.43 M | 248 | 230 | 315 | 393 | 394 |
HLA-B | 1.43 M | 325 | 293 | 431 | 688 | 921 |
HLA-C | 1.43 M | 285 | 255 | 391 | 697 | 1001 |
HLA-DRB1 | 1.43 M | 1011 | 364 | 702 | 1254 | 1806 |
HLA-DQB1 | 1.43 M | 941 | 464 | 830 | 1443 | 2055 |
HLA-DPB1 | 1.43 M | 864 | 313 | 615 | 1088 | 1561 |