Fig. 2

Protein family diversity. 2.1. Diversity in MosquitoSlim categories. For each node, gains, losses (if any), and enriched gains (if any) are shown. Each color present in the stacked column indicates that at least one protein family in that category was detected at the associated node, and each color absent indicates the lack of protein families in that category. MosquitoSlim KEY: a Related to nucleic acid metabolism, b Metabolic process, c Innate immunity, d Cell cycle, e Binding, f Cuticular protein, g Chemosensation, h Other, i Cellular component biogenesis j Cellular membrane, k Insecticide resistance, l Peptide hormones, m Epigenetic. 2.2. Diversity in other annotation methodologies. Each color represents a different database, and the height of each individual block in the column reflects the number of distinct categories. For example, Node 2 has protein family gains that were assigned to 16 different KEGG objects, 70 different InterPro groups, and 61 different InterPro2GO terms