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Fig. 6 | BMC Genomics

Fig. 6

From: Segmental duplications and evolutionary acquisition of UV damage response in the SPATA31 gene family of primates and humans

Fig. 6

Increased UV sensitivity of mutated HFF cells. To assess the UVC sensitivity, we used the LDH cytotoxicity assay to measure the release of LDH from damaged or dead cells. This is a very sensitive cell toxicity test [37] and [38]. a Differences between controls and mutated cells between the two types of mutated cell lines, Cl1 (low) and Cl2 (high) and non-mutated control cells. b Differences between the low copy cell line HFF2450 and the high copy cell line HFF2703. P-values of Student’s t test are indicated as * < 0.05, ** < 0.01, and *** < 0.001

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