Fig. 5

Sex-specific patterns of temporal regulation. a: heatmap for the complete set of 68 transcripts that show significant sex-specific patterns of change in expression at one or more ages. Samples (columns) are arranged by age group, with females and males also grouped together within age groups. Relative expression values for individual genes are organized into rows. Relative expression values for each gene were calculated by dividing the normalized count value for each sample by the mean of count values for that gene across all samples. The result was then log2 transformed and used for shading. The majority of these transcripts are up-regulated through development in males relative to females. b: GO enrichment treemap for genes shown in heatmap. c: Transcript expression profiles for the 8 heat-shock proteins found to change over time in a sex-specific manner in this comparison. Lines are drawn through the mean count level at each age point for both females and males in pink and blue, respectively