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Table 5 KEGG pathways identified for the upregulated genes in the high-RFI group with an FDR q-value < 0.01 from the output of the GSEA in the Jerseys

From: RNA-Seq transcriptomics and pathway analyses reveal potential regulatory genes and molecular mechanisms in high- and low-residual feed intake in Nordic dairy cattle

 

Pathways name

FDR q-value

Core enrichment gene

1

Retinol metabolism

0.002

PNPLA4, CYP2B6, CYP2C18, RETSAT, CYP1A1, RDH11, CYP1A2, ALDH1A1, CYP26B1, LRAT, ADH5, UGT2A3, RDH16, UGT1A1, ALDH1A2, RDH10

2

Metabolism of xenobiotics by cytochrome P450

0.003

CYP2B6, ALDH1A3, CYP2E1, CYP2C18, EPHX1, CYP1A1, CYP1A2, MGST1, MGST3, ALDH3B1, ADH5, UGT2A3, UGT1A1

3

Ether lipid metabolism

0.009

ENPP6, PLA2G7, PLD2ENPP2, LPCAT2PLA2G12A, AGPSPLD1

  1. FDR q-value = adjusted p-value; core enrichment gene = subset of genes that contributes most to the enrichment result