Fig. 3

Comparison of differential gene expression observed in the prediagnostic study and the results of the meta-analysis of clinical studies. Solid lines are placed at p values of significance threshold after Bonferroni correction. Dashed lines correspond to p value = 0.05. Solid red circles represent significant genes after Bonferroni correction in both the prediagnostic study and meta-analysis on clinical studies. Spearman rank correlation between signed –log 10 p values was 0.53