Fig. 3

Simulated development of the frequencies of lethal/incompatible alleles/haplotypes during 100 generations (t) of random mating given an overdominance model (green line), a sex-neutral pseudooverdominance model (red line) or a sex-dependent pseudooverdominance model (blue). Scenarios included simulations of two alleles (a) and ten alleles (b) where all alleles, whether lethal/incompatible or not, exhibited equal initial allele frequencies (0.5 and 0.1 respectively). The pseudooverdominance model for two alleles is in effect equivalent to a model with a single lethal recessive allele. The stability of the overdominance model was further assessed by performing a simulation of ten alleles where initial frequencies varied (c) spanning a range from 0.01 to 0.3 at t = 0. Note: The frequency of the W-gametolog is discounted from allele frequencies of the sex-dependent models and sex-dependent and sex-neutral versions of the overdominance model behaved identically