Analysis of hepatic transcript profile and plasma lipid profile in early lactating dairy cows fed grape seed and grape marc meal extract

Table 3 The most strongly differentially regulated (FC > 1.3 or FC < −1.3 and P < 0.05) miRNAs in the liver of cows fed grape seed and grape marc meal extract (GSGME) versus control cows at 1 week postpartum

Gene symbol	micro RNA description	FC^a	P-value
MIR376C	microRNA mir-376c	1.40	0.027
MIR365-2	microRNA mir-365–2	–1.31	0.010
MIR2345	microRNA mir-2345	–1.33	0.007
MIR2403	microRNA mir-2403	–1.34	0.029
MIR2462	microRNA mir-2462	–1.39	0.006
MIR2359	microRNA mir-2359	–1.41	0.002
MIR2430	microRNA mir-2430	–1.51	0.004
MIR2461	microRNA mir-2461	–1.53	0.010
MIR365	microRNA mir-365	–1.56	0.003

^aThe FC was calculated from the signal log ratios as follows: 2^{Signal log ratio} if signal log ratio ≥ 0 and (−1) × 2^{–(Signal log ratio)} if signal log ratio < 0. Signal log ratios were calculated from n = 6 microarrays per group

ISSN: 1471-2164