GO termsa | Nb DEG | E score | p-value | Clustered DEG |
---|---|---|---|---|
GO:0046907 ~ intracellular transport | 17 | 2.06 | <0.001 | PSEN1, YWHAZ, TOMM5, MLX, DST, RAB35, PIKFYVE, MYL6, PEX6, STAM2, OPTN, CDK5, CCHCR1, YWHAG, JAK2, STAM, NUP43 |
(GO:0015031 ~ protein transport) | (13) | (0.025) | ||
GO:0006955 ~ immune response | 13 | 1.81 | 0.050 | HLA-A, HLA-B, HLA-C, HLA-H, CTSC, YWHAZ, PSEN1, TRAF6, POLR3B, BST1, COL4A3BP, ADAM17, XCL1 |
(GO:0048002 ~ antigen processing and presentation of antigen) | (4) | (0.001) | ||
GO:0006643 ~ membrane lipid metabolic process | 4 | 1.43 | 0.030 | CLN3, PSAP, SGMS1, COL4A3BP |
GO:0009057 ~ macromolecule catabolic process | 17 | 1.14 | 0.005 | PSEN1, YME1L1,CD40, TRAF6, USP33, USP30, UBE2V1, PSMA3, PSMD1, MUTYH, CLN3, TMEM189, CDK5, RNASET2, NEURL2, ADAM9, ADAM17 |
(GO:0030163 ~ protein catabolic process) | (12) | (0.015) | ||
GO:0006414 ~ translational elongation | 4 | 1.13 | 0.052 | RPL6, RPL14, RPS18, RPL35 |
GO:0008219 ~ cell death | 14 | 1.08 | 0.007 | PSEN1, NTN1, CD40, TRAF6, SOD2, YWHAG, POLR3D, HSPE1, CLN3, TRIO, SGMS1, OPTN, PDCD4, CDK5, JAK2, BLCAP, ADAM9, ADAM17 |
GO:0045859 ~ regulation of protein kinase activity | 9 | 0.008 | ||
GO:0001819 ~ positive regulation of cytokine production | 5 | 0.007 | ||
GO:0006644 ~ phospholipid metabolic process | 6 | 1.06 | 0.021 | PON1, PIGL, PLA2G12A, SGMS1, PIKFYVE, CLN3 |
GO:0006979 ~ response to oxidative stress | 6 | 1.00 | 0.048 | PSEN1, SOD2, GPX3, JAK2, ADAM9, MUTYH |