Table 4 Summary of the main muscle-specific biological processes
GO termsa | Nb DEG | E score | P-value |
|---|---|---|---|
Over-expressed in pigs from the low RFI line | |||
GO:0006412 ~ translation | 97 | 39.8 | <0.001 |
GO:0022613 ~ ribonucleoprotein complex biogenesis | 33 | 4.3 | <0.001 |
GO:0003012 ~ muscle system contraction process | 26 | 4.1 | <0.001 |
GO:0006091 ~ generation of precursor metabolites and energy | 31 | 3.1 | <0.001 |
(GO:0006006 ~ glucose metabolic process) | (26) | (0.007) | |
GO:0032268 ~ regulation of cellular protein metabolic process | 52 | 2.8 | 0.001 |
(GO:0006417 ~ regulation of translation) | (23) | (<0.001) | |
GO:0030163 ~ protein catabolic process | 67 | 2.7 | <0.001 |
(GO:0006511 ~ ubiquitin-dependent catabolic process) | (28) | (0.010) | |
GO:0008104 ~ protein localization | 84 | 2.7 | 0.003 |
(GO:0046907 ~ intracellular transport) | (73) | (<0.001) | |
GO:0005977 ~ glycogen metabolic process | 8 | 1.6 | 0.009 |
GO:0046324 ~ regulation of glucose import | 10 | 1.5 | <0.001 |
Under-expressed in pigs from the low RFI line | |||
GO:0006955 ~ immune response | 62 | 10.1 | <0.001 |
GO:0002250 ~ adaptive immune response | 18 | 5.4 | <0.001 |
GO:0001817 ~ regulation of cytokine production | 22 | 4.6 | <0.001 |
GO:0010033 ~ response to organic substance | 61 | 4.0 | <0.001 |
GO:0070482 ~ response to oxygen levels | 17 | 4.0 | <0.001 |
GO:0001501 ~ skeletal system development | 25 | 3.4 | <0.001 |
GO:0042981 ~ regulation of apoptosis | 55 | 3.0 | <0.001 |
GO:0009743 ~ response to carbohydrate stimulus | 10 | 2.1 | <0.001 |
GO:0006631 ~ fatty acid metabolic process | 27 | 1.7 | 0.006 |
(GO:0008610 ~ lipid biosynthetic process) | (19) | (0.05) | |