Skip to main content

Table 2 Genes repressed by forced Klf9 expression in HT22 [TR/TO-Klf9] cells and genes with Klf9 peaks associated in HT22 [BirA/FLBIO-Klf9] cells were subjected to pathway analysis using GeneCoDis

From: The Krüppel-like factor 9 cistrome in mouse hippocampal neurons reveals predominant transcriptional repression via proximal promoter binding

Panther ID Pathway Number of Klf9 target genes in pathway Adjusted p value
All enriched pathways among genes repressed by Klf9
 Panther:P00016 Cytoskeletal regulation by Rho GTPase 3 0.034087
 Panther:P00031 Inflammation mediated by chemokine and cytokine signaling pathway 5 0.041865
 Panther:P00057 Wnt signaling pathway 5 0.041865
 Panther:P00010 B cell activation 3 0.046343
The top ten most enriched pathways among genes with Klf9 peaks associateda
 Panther:P00006 Apoptosis signaling pathway 31 8.67E-11
 Panther:P00034 Integrin signalling pathway 36 2.79E-10
 Panther:P00031 Inflammation mediated by chemokine and cytokine signaling pathway 46 3.16E-10
 Panther:P00016 Cytoskeletal regulation by Rho GTPase 23 1.28E-09
 Panther:P00005 Angiogenesis 33 1.51E-09
 Panther:P00057 Wnt signaling pathway 42 1.75E-08
 Panther:P00056 VEGF signaling pathway 19 2.64E-08
 Panther:P00047 PDGF signaling pathway 28 2.82E-08
 Panther:P04393 Ras Pathway 20 7.85E-08
 Panther:P00021 FGF signaling pathway 24 4.71E-07
  1. Pathways are ordered from most- to least-enriched based on the false discovery rate (FDR)-adjusted p value
  2. a A complete list of enriched pathways is given in Additional file 16: Table S7