Table 2 Genes repressed by forced Klf9 expression in HT22 [TR/TO-Klf9] cells and genes with Klf9 peaks associated in HT22 [BirA/FLBIO-Klf9] cells were subjected to pathway analysis using GeneCoDis
Panther ID | Pathway | Number of Klf9 target genes in pathway | Adjusted p value |
|---|---|---|---|
All enriched pathways among genes repressed by Klf9 | |||
Panther:P00016 | Cytoskeletal regulation by Rho GTPase | 3 | 0.034087 |
Panther:P00031 | Inflammation mediated by chemokine and cytokine signaling pathway | 5 | 0.041865 |
Panther:P00057 | Wnt signaling pathway | 5 | 0.041865 |
Panther:P00010 | B cell activation | 3 | 0.046343 |
The top ten most enriched pathways among genes with Klf9 peaks associateda | |||
Panther:P00006 | Apoptosis signaling pathway | 31 | 8.67E-11 |
Panther:P00034 | Integrin signalling pathway | 36 | 2.79E-10 |
Panther:P00031 | Inflammation mediated by chemokine and cytokine signaling pathway | 46 | 3.16E-10 |
Panther:P00016 | Cytoskeletal regulation by Rho GTPase | 23 | 1.28E-09 |
Panther:P00005 | Angiogenesis | 33 | 1.51E-09 |
Panther:P00057 | Wnt signaling pathway | 42 | 1.75E-08 |
Panther:P00056 | VEGF signaling pathway | 19 | 2.64E-08 |
Panther:P00047 | PDGF signaling pathway | 28 | 2.82E-08 |
Panther:P04393 | Ras Pathway | 20 | 7.85E-08 |
Panther:P00021 | FGF signaling pathway | 24 | 4.71E-07 |