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Fig. 3 | BMC Genomics

Fig. 3

From: Detect tissue heterogeneity in gene expression data with BioQC

Fig. 3

BioQC reveals sample clustering and tissue heterogeneity of small-intestine samples in GTEx a Tissue enrichment scores reported by BioQC when applied to small-intestine samples in GTEx. Samples are shown in columns and clustered by correlation-based hierarchical clustering. Ten tissue signatures with the highest average scores are shown in rows. Expression profiles of selected tissue signatures (with bold row names) in representative samples (in yellow boxes) are visualized below. The representative samples are labeled by the last five digits/letters of respective GTEx sample identifiers. be Whisker-box-plots of genes enriched in small intestine, lymphocytes, and cardiac muscle in representative samples. Each dot represents one signature gene. Dash lines indicate RPKM equal to one which represents an arbitrary threshold of low gene expression. RPKM: Reads Per Kilobase per Million mapped reads

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