TY - JOUR AU - Diaz-Beltran, Leticia AU - Esteban, Francisco J. AU - Varma, Maya AU - Ortuzk, Alp AU - David, Maude AU - Wall, Dennis P. PY - 2017 DA - 2017/04/20 TI - Cross-disorder comparative analysis of comorbid conditions reveals novel autism candidate genes JO - BMC Genomics SP - 315 VL - 18 IS - 1 AB - Numerous studies have highlighted the elevated degree of comorbidity associated with autism spectrum disorder (ASD). These comorbid conditions may add further impairments to individuals with autism and are substantially more prevalent compared to neurotypical populations. These high rates of comorbidity are not surprising taking into account the overlap of symptoms that ASD shares with other pathologies. From a research perspective, this suggests common molecular mechanisms involved in these conditions. Therefore, identifying crucial genes in the overlap between ASD and these comorbid disorders may help unravel the common biological processes involved and, ultimately, shed some light in the understanding of autism etiology. SN - 1471-2164 UR - https://doi.org/10.1186/s12864-017-3667-9 DO - 10.1186/s12864-017-3667-9 ID - Diaz-Beltran2017 ER -