Table 3 List of the 19 candidate genes significantly differentially expressed in the three experiments and the disorders where they are implicated
From: Cross-disorder comparative analysis of comorbid conditions reveals novel autism candidate genes
Genes | Sibling disorders | # Disorders |
|---|---|---|
ADAM10 | Bipolar Spectrum Disorders, Down Syndrome, Sleep Disorders | 3 |
ADCY9 | Bipolar Spectrum Disorders, Depressive Disorder, Epilepsy, Schizophrenia, Sleep Disorders | 5 |
ADCYAP1R1 | Anxiety Disorder, Bipolar Spectrum Disorders, Obsessive Compulsive Disorder, Panic Disorder | 4 |
AKT1 | Bipolar Spectrum Disorders, Depressive Disorder, Epilepsy, Fragile X Syndrome, Schizophrenia, Tuberous Sclerosis | 6 |
ATN1 | Epilepsy, Fragile X Syndrome, Intellectual Disability, Schizophrenia, Sleep Disorders | 5 |
DGCR8 | Depressive Disorder, Fragile X Syndrome, Schizophrenia, Sleep Disorders | 4 |
DLGAP4 | Anxiety Disorder, Bipolar Spectrum Disorders, Obsessive Compulsive Disorder, Panic Disorder, Schizophrenia, Sleep Disorders | 6 |
HSPA1L | Bipolar Spectrum Disorders, Depressive Disorder, Schizophrenia | 3 |
KCNH2 | Epilepsy, Intellectual Disability, Schizophrenia, Sleep Disorders | 4 |
MEGF10 | Bipolar Spectrum Disorders, Schizophrenia, Sleep Disorders | 3 |
MMP2 | Epilepsy, Sleep Disorders, Tuberous Sclerosis | 3 |
NDE1 | Bipolar Spectrum Disorders, Epilepsy, Intellectual Disability, Schizophrenia | 4 |
NPPB | Anxiety Disorder, Bipolar Spectrum Disorders, Obsessive Compulsive Disorder, Panic Disorder, Sleep Disorders | 5 |
NRP1 | Anxiety Disorder, Bipolar Spectrum Disorders, Obsessive Compulsive Disorder, Panic Disorder, Sleep Disorders | 5 |
PPP3CB | Attention Deficit Hyperactivity Disorder, Schizophrenia, Sleep Disorders | 3 |
PRKG1 | Attention Deficit Hyperactivity Disorder, Fragile X Syndrome, Schizophrenia, Sleep Disorders | 4 |
SLC29A2 | Depressive Disorder, Epilepsy, Sleep Disorders | 3 |
SMARCA2 | Epilepsy, Intellectual Disability, Schizophrenia, Sleep Disorders | 4 |
VIPR2 | Anxiety Disorder, Bipolar Spectrum Disorders, Depressive Disorder, Down Syndrome, Epilepsy, Intellectual Disability, Obsessive Compulsive Disorder, Panic Disorder, Schizophrenia | 9 |