Table 2 Spearman rank correlation coefficients (ρ) between the transcript/protein categorical R2 values and possible sources of variation
From: The predictive nature of transcript expression levels on protein expression in adult human brain
Biological Process | Molecular Function | Cellular Compartment | ||
|---|---|---|---|---|
Category Size | All categories | −0.08 | −0.05 | −0.25** |
Categories with < 20 transcript/protein pairs | −0.05 | −0.05 | −0.26 | |
Categories with ≥ 20 transcript/protein pairs | 0.03 | −0.22* | −0.19 | |
Abundance | Mean gene expression | −0.09 | −0.17 | 0.10 |
Mean protein expression | −0.07 | 0.15 | 0.04 | |
Gene Length | All categories | 0.05 | −0.03 | 0.11 |
Synthesis/degradation | Transcription rate | 0.17* | −0.31** | −0.29* |
Translation rate | 0.13 | 0.29** | −0.30** | |
mRNA half-life | −0.10 | −0.36** | 0.26* | |
Protein half-life | 0.12 | 0.05 | −0.24 |