Skip to main content

Table 4 KEGG pathway enrichment analysis of common genes in SD regions among domestic species

From: Characterization of genome-wide segmental duplications reveals a common genomic feature of association with immunity among domestic animals

KEGG Term

Description

Count

P-Value

Fold Enrichment

Bonferroni

hsa00980

Metabolism of xenobiotics by cytochrome P450

22

8.33E-20

14.92

7.00E-18

hsa00982

Drug metabolism

22

1.84E-19

14.43

1.55E-17

hsa00830

Retinol metabolism

20

4.83E-18

15.07

4.05E-16

hsa00983

Drug metabolism

16

2.32E-14

15.14

1.95E-12

hsa00140

Steroid hormone biosynthesis

16

7.37E-14

14.15

6.18E-12

hsa05320

Autoimmune thyroid disease

15

7.57E-12

11.96

6.36E-10

hsa04740

Olfactory transduction

35

7.62E-12

3.76

6.40E-10

hsa04140

Regulation of autophagy

13

1.34E-11

15.11

1.13E-09

hsa04623

Cytosolic DNA-sensing pathway

14

3.49E-10

10.35

2.93E-08

hsa04612

Antigen processing and presentation

16

8.22E-10

7.84

6.90E-08

hsa04622

RIG-I-like receptor signaling pathway

14

1.01E-08

8.02

8.45E-07

hsa00053

Ascorbate and aldarate metabolism

8

6.88E-08

19.14

5.78E-06

hsa00040

Pentose and glucuronate interconversions

8

1.10E-07

18.08

9.26E-06

hsa04620

Toll-like receptor signaling pathway

14

7.61E-07

5.64

6.39E-05

hsa00150

Androgen and estrogen metabolism

9

2.13E-06

9.90

1.79E-04

hsa00500

Starch and sucrose metabolism

9

5.87E-06

8.72

4.93E-04

hsa00860

Porphyrin and chlorophyll metabolism

8

1.09E-05

9.86

0.000916

hsa04650

Natural killer cell mediated cytotoxicity

14

1.72E-05

4.28

0.001442

hsa00591

Linoleic acid metabolism

7

4.52E-05

10.17

0.003790

hsa04630

Jak-STAT signaling pathway

14

8.71E-05

3.67

0.007294