Fig. 5

a) GO enrichment for cellular component, according to PANTHER analysis, for the differentially abundant proteins during neural differentiation of ES cells. The results are represented as –log p-value (left axis) and fold enrichment (right axis) for each category using Mus musculus as reference. The GO terms were clustered based on similarity. b) GO slim enrichment terms related to molecular function and biological process categories, calculated with BiNGO on Cytoscape, using the full interactome data set. Circle size is proportional to the frequency of the GO term, while colour indicates the –log p-value (orange for higher, yellow for lower). GO terms in blue represent the ones also found significant when testing only the differentially abundant proteins