Fig. 3

Clusters of orthologous groups (COG) of mutated genes of Lactobacillus casei Zhang during long-term cultivation in lactic acid bacteria susceptibility test medium (LSM) with and without antibiotics. Functional categories: [C], Energy production and conversion; [E], Amino acid transport and metabolism; [F], Nucleotide transport and metabolism; [G], Carbohydrate transport and metabolism; [H], Coenzyme transport and metabolism; [I], Lipid transport and metabolism; [J], Translation, ribosomal structure and biogenesis; [K], Transcription; [L], Replication, recombination and repair; [M], Cell wall/membrane/envelope biogenesis; [O], Posttranslational modification, protein turnover, chaperones; [P], Inorganic ion transport and metabolism; [Q], Secondary metabolites biosynthesis, transport and catabolism; [R], General function prediction only; [S], Function unknown; [T], Signal transduction mechanisms; [V], Defense mechanisms