Table 1 Selected genes upregulated in the hindgut following cold acclimation whose putative function in relation to cold tolerance is discussed in the text
Function | Description | Fold change | P-value | Species |
|---|---|---|---|---|
Apoptosis | Caspase-6 | 4.0 | 1.8E-31 | Gs |
Caspase-8 | 4.0 | 9.1E-39 | Zn | |
Circadian | Clock | 2.7 | 1.7E-17 | Gb |
Nocturnin | 2.4 | 1.8E-16 | Zn | |
Period | 7.4 | 1.6E-50 | Gb | |
Cytoskeleton | Microtubule-Associated Protein Jupiter | 4.2 | 5.3E-31 | Zn |
Diuresis | Atrial Natriuretic Peptide-Converting Enzyme | 3.5 | 3.7E-15 | Zn |
Ion transport | Ca2+ Release-Activated Ca2+ Channel Protein 1 | 2.3 | 4.3E-17 | Zn |
Na+-K+ ATPase Alpha Subunit | 2.8 | 2.7E-21 | Ll | |
Neurotransmission | Na+- and Cl--Dependent GABA Transporter Ine | 2.1 | 8.8E-10 | Md |
Phosphorylation | Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase 2 | 2.7 | 2.2E-04 | Zn |
Serine Threonine-Protein Kinase Rio3 | 2.9 | 3.7E-07 | Zn | |
Serine Threonine-Protein Kinase Sik3-Like Isoform X3 | 2.9 | 8.7E-16 | Ap | |
Protein folding/chaperone | Heat Shock Protein 90 | 3.0 | 1.7E-28 | Gf |
Hsp70 Family Member | 2.1 | 8.0E-14 | Lm | |
Repair/detoxicant/antioxidant | Cytochrome P450 | 26.0 | 7.7E-108 | Aa |
Cytochrome P450 4C1 | 2.0 | 7.2E-05 | Zn | |
DNA Mismatch Repair Protein Mlh1 | 3.5 | 1.2E-22 | Xt | |
DNA Repair Protein Complementing Xp-G Cells | 2.7 | 4.8E-20 | Zn | |
Glutathione S-Transferase D7 | 2.1 | 2.6E-05 | Zn | |
Signal transduction | cAMP-Specific 3’,5’-Cyclic Phosphodiesterase, Isoform F Isoform X2 | 2.1 | 3.3E-12 | Tc |
Dual 3’,5’ Cyclic-AMP and -GMP Phosphodiesterase 11 | 2.5 | 1.5E-17 | Zn | |
G Kinase-Anchoring Protein 1 | 3.8 | 6.5E-34 | Zn | |
G-Protein Coupled Receptor Mth2-Like | 2.2 | 4.5E-14 | Ap | |
Protein Kinase C Iota (partial) | 2.4 | 1.5E-16 | Zn | |
Signalling/gut contraction | Adenylate Cyclase Type (partial) | 2.5 | 1.2E-13 | Zn |