Table 4 Selected downregulated genes in the Malpighian tubules following cold acclimation whose putative function in relation to cold tolerance is discussed in the text
Function | Description | Fold change | P-value | Species |
|---|---|---|---|---|
Autophagy | Autophagy-Related Protein 2-Like Protein B | -2.1 | 1.5E-7 | Zn |
Circadian | Timeless | -3.0 | 3.3E-13 | Gb |
Cytoskeleton | Microtubule-Associated Proteins 1A 1B Light Chain 3C | -4.9 | 8.5E-23 | Zn |
Epidermal Growth Factor Receptor Kinase Substrate 8-Like Isoform X1 | -2.4 | 1.9E-9 | Md | |
Gamma-Tubulin Complex Component 3 | -2.0 | 4.7E-9 | Zn | |
Development | Juvenile Hormone-Inducible | -10.6 | 3.8E-50 | Aa |
Ion transport/pH regulation | Carbonic Anhydrase 9 | -4.2 | 2.1E-33 | Zn |
Carbonic Anhydrase 1 | -2.2 | 5.9E-15 | Tc | |
V-ATPase Subunit D | -2.1 | 1.2E-14 | Lm | |
Phosphorylation | Inositol Monophosphatase | -6.9 | 1.1E-58 | Zn |
Serine Threonine-Protein Phosphatase 2B Catalytic Subunit 2-Like Isoform X2 | -2.1 | 9.0E-14 | Tc | |
Protein folding/chaperone | Heat Shock Protein 67B2 | -2.8 | 1.6E-16 | Zn |
Repair/detoxicant/antioxidant | Antioxidant Enzyme | -2.9 | 3.7E-23 | Go |
Cytochrome P450 | -2.9 | 1.4E-11 | Bt | |
Cytochrome P450 4C1 | -2.7 | 3.2E-22 | Zn | |
Cytochrome P450 6A14 | -2.5 | 3.2E-13 | Zn | |
Cytochrome P450 9E2 | -2.3 | 1.4E-11 | Zn | |
Cytochrome P450 (partial) | -2.3 | 3.6E-12 | Zn | |
Cytochrome P450 9E1 | -2.2 | 3.3E-14 | Dp | |
Glutathione S-Transferase | -3.2 | 1.8E-23 | Bt | |
Glutathione S-Transferase Theta 1 | -3.1 | 1.9E-28 | Lm |