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Fig. 1 | BMC Genomics

Fig. 1

From: Growth and stress response mechanisms underlying post-feeding regenerative organ growth in the Burmese python

Fig. 1

Conceptual overview of differences between Canonical Pathway Analysis (CPA) and Upstream Regulatory Molecule Analysis (URMA). Pairwise analyses on experimental gene expression data (a) identify significantly upregulated and downregulated genes (b). Significantly differentially expressed genes are then analyzed in two distinct IPA analyses (CPA and URMA) (c) Canonical Pathway Analysis predicts pathway activation based on overlap of gene expression data with molecules within the pathway. d Upstream Regulatory Molecule Analysis predicts activation of specific regulatory molecules based on downstream molecules in our gene expression dataset

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