Table 3 Summary of the largest effect QTL detected for RFI in U.S. Angus, Hereford, and SimAngus beef cattle
From: Genome-wide association study for feed efficiency and growth traits in U.S. beef cattle
RFI | Position (Chr_Mb) | -log10 P-value | Regression Beta | PVE | Proximal Positional Candidate Gene(s) | Scientific Precedence [reference]; organism; trait |
|---|---|---|---|---|---|---|
Angus | 2_30 | 5.51 | 0.51 | 0.033 | XIRP2 | [28]; cattle; feed efficiency and growth |
11_80 | 4.78 | −0.45 | 0.028 | NT5C1B/RDH1 | NA | |
17_58 | 4.77 | −1.01 | 0.028 | HSPB8 | [29]; human; obesity traits | |
8_13 | 4.74 | −0.88 | 0.028 | LOC104969273/LOC104969276 | NA | |
14_27 | 4.56 | −0.43 | 0.027 | TOX/TRNAC-GCA | [30]; human; adiposity | |
29_40 | 4.55 | 0.47 | 0.027 | DDB1/DAK | [31,32,33,34,35]; human, chicken, duck, pig; cell cycle, feed efficiency and growth | |
12_91 | 4.39 | 1.48 | 0.025 | ADPRHL1/CDC-16 | ||
Hereford | 6_113 | 6.51 | 1.03 | 0.031 | RAB28 | [40]; human; obesity-related traits |
19_54 | 6.45 | −0.55 | 0.031 | DNAH17 | [41]; human; adipogenic differentiation | |
3_29 | 4.45 | −0.82 | 0.020 | PTPN22/RBSBN1 | [27]; human; diabetes, arthritis | |
1_72 | 4.34 | 0.77 | 0.020 | DLG1 | [42]; human; glucose uptake | |
SimAngus | 15_84 | 5.90 | −0.42 | 0.020 | STX3/MRPL16/GIF/TCN1 | [43,44,45,46]; human, mice, cattle; obesity, glucose levels, growth |
29_20 | 5.46 | 0.58 | 0.018 | LOC101906936/LUZP2 | [47]; human; serum magnesium levels | |
15_82 | 5.16 | 0.39 | 0.017 | OR9Q2 | [50]; pig; feed efficiency | |
8_97 | 4.96 | −0.56 | 0.016 | LOC101903458 | NA | |
22_57 | 4.67 | −0.56 | 0.015 | TMEM40 | ||
13_44 | 4.51 | 0.58 | 0.014 | UCN3/CST7 |