From: Genome-wide association study for feed efficiency and growth traits in U.S. beef cattle
DMI | Position (Chr_Mb) | -log10 P-value | Regression Beta | PVE | Proximal/Putative Candidate Gene(s) | Scientific Precedence [reference]; organism; trait |
---|---|---|---|---|---|---|
Angus | 8_107 | 6.53 | −2.91 | 0.039 | LOC101902746/TNC | [55]; cattle; feed efficiency |
11_97 | 5.81 | 2.47 | 0.034 | MVB12B/LMX1B | [56]; human; obesity traits | |
2_63 | 5.26 | −0.74 | 0.031 | TMEM163/MGAT5 | ||
1_106 | 5.25 | 0.67 | 0.031 | LOC782622/LOC785220 | NA | |
7_27 | 4.89 | −2.09 | 0.029 | SLC12A2 | [11]; cattle; feed efficiency | |
11_7 | 4.88 | 0.89 | 0.028 | IL1R2 | [55]; cattle; feed efficiency | |
17_57 | 4.72 | 0.78 | 0.027 | CUX2 | [57]; human; diabetes | |
9_90 | 4.68 | −0.57 | 0.027 | ESR1 | ||
Hereford | 3_70 | 5.56 | 0.76 | 0.026 | TYW3/CRYZ | [67]; human; insulin resistance |
19_55 | 5.48 | 0.79 | 0.026 | MGAT5B | [68]; mice; glycosylation | |
24_41 | 5.35 | −0.98 | 0.025 | RAB12 | [69]; mice; cellular nutrient sensing | |
3_73 | 5.35 | 0.98 | 0.025 | NEGR1 | ||
19_57 | 5.09 | −0.92 | 0.024 | RAB37 | [73]; mice; insulin release | |
10_47 | 4.81 | 0.91 | 0.022 | CA12/LACTB | ||
SimAngus | 14_17 | 5.68 | −1.05 | 0.019 | NDUFB9/RNF139/MTSS1/SQLE | [28, 82,83,84,85]; cattle, human, mice; feed efficiency, diabetes, obesity |
21_16 | 5.36 | −0.49 | 0.018 | SV2B | ||
3_22 | 5.01 | −0.49 | 0.016 | LOC104971520/CHD1L/LOC788724/FMO5 | [88]; mice; obesity and diabetes | |
26_14 | 4.70 | 0.50 | 0.015 | IDE/CYP26A1 | [89,90,91]; humans, mice; insulin degradation, diabetes, obesity | |
15_58 | 4.50 | 0.59 | 0.014 | CAPN5/MYO7A | ||
6_91 | 4.49 | −0.45 | 0.014 | CXCL1 | [94]; mice; diet-induced obesity | |
2_47 | 4.39 | −0.50 | 0.014 | LYPD6 | [55]; cattle; feed efficiency |