Prediction of gene expression with cis-SNPs using mixed models and regularization methods

BMC Genomics

Table 2 Number of predictive genes passing the given R ² threshold in the Geuvadis data and GenoExp data

There are 15,810 and 15,427 genes in the Geuvadis data and GenoExp data, respectively. It can be seen that in both data sets when the given R ² threshold is large (e.g. ≥0.30) the number of predictive genes passing that value in LMM is less than that of LASSO, ENET or BSLMM, implying that these highly predictive genes may have a sparse genetic architecture

ISSN: 1471-2164