Skip to main content

Table 1 Association of expression modules with tumour stage and RFS in the discovery and validation datasets

From: Associating transcriptional modules with colon cancer survival through weighted gene co-expression network analysis

Modules Total gene count Correlation with tumour stage Association with RFS in the discovery dataset
(n = 461)
Association with RFS in the validation dataset
(n = 111)
R p-value HR CI p-value FDR HR CI p-value
Magenta 41 −0.07 1.46 × 10−1 0.84 0.63–1.13 2.52 × 10−1 3.90 × 10−1 0.55 0.30–1.00 5.13 × 10−2
Tan 35 0.05 3.21 × 10−1 0.82 0.60–1.12 2.11 × 10−1 3.86 × 10−1 1.38 0.73–2.59 3.20 × 10−1
Green 170 −0.14 2.64 × 10−3 0.59 0.42–0.81 1.37 × 10−3 7.52 × 10−3 0.51 0.25–1.05 6.67 × 10−2
Yellow 179 −0.05 2.62 × 10−1 0.59 0.43–0.81 9.60 × 10−4 7.52 × 10−3 0.70 0.37–1.34 2.82 × 10−1
Black 82 0.07 1.34 × 10−1 0.85 0.62–1.17 3.22 × 10−1 3.94 × 10−1 0.59 0.29–1.19 1.42 × 10−1
Purple 48 0.00 9.64 × 10−1 1.03 0.77–1.39 8.44 × 10−1 8.44 × 10−1 0.64 0.34–1.21 1.70 × 10−1
Brown 866 0.10 3.15 × 10−2 1.36 0.97–1.92 7.68 × 10−2 2.11 × 10−1 2.11 1.22–3.64 7.57 × 10−3
Red 108 0.11 2.12 × 10−2 1.33 0.94–1.87 1.03 × 10−1 2.27 × 10−1 1.12 0.58–2.14 7.36 × 10−1
Green-yellow 44 −0.03 5.29 × 10−1 0.84 0.61–1.16 2.84 × 10−1 3.90 × 10−1 1.27 0.70–2.29 4.35 × 10−1
Blue 369 0.04 4.32 × 10−1 0.93 0.66–1.32 6.99 × 10−1 7.69 × 10−1 1.56 0.80–3.01 1.89 × 10−1
Pink 52 0.03 5.91 × 10−1 0.65 0.47–0.91 1.08 × 10−2 3.97 × 10−2 1.35 0.72–2.53 3.50 × 10−1
  1. CI 95% confidence interval, RFS recurrence-free survival. Hazard ratios (HRs), 95% CI, and p-values were calculated using Cox proportional hazard regression analysis