Table 1 Association of expression modules with tumour stage and RFS in the discovery and validation datasets
Modules | Total gene count | Correlation with tumour stage | Association with RFS in the discovery dataset (n = 461) | Association with RFS in the validation dataset (n = 111) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
R | p-value | HR | CI | p-value | FDR | HR | CI | p-value | ||
Magenta | 41 | −0.07 | 1.46 × 10−1 | 0.84 | 0.63–1.13 | 2.52 × 10−1 | 3.90 × 10−1 | 0.55 | 0.30–1.00 | 5.13 × 10−2 |
Tan | 35 | 0.05 | 3.21 × 10−1 | 0.82 | 0.60–1.12 | 2.11 × 10−1 | 3.86 × 10−1 | 1.38 | 0.73–2.59 | 3.20 × 10−1 |
Green | 170 | −0.14 | 2.64 × 10−3 | 0.59 | 0.42–0.81 | 1.37 × 10−3 | 7.52 × 10−3 | 0.51 | 0.25–1.05 | 6.67 × 10−2 |
Yellow | 179 | −0.05 | 2.62 × 10−1 | 0.59 | 0.43–0.81 | 9.60 × 10−4 | 7.52 × 10−3 | 0.70 | 0.37–1.34 | 2.82 × 10−1 |
Black | 82 | 0.07 | 1.34 × 10−1 | 0.85 | 0.62–1.17 | 3.22 × 10−1 | 3.94 × 10−1 | 0.59 | 0.29–1.19 | 1.42 × 10−1 |
Purple | 48 | 0.00 | 9.64 × 10−1 | 1.03 | 0.77–1.39 | 8.44 × 10−1 | 8.44 × 10−1 | 0.64 | 0.34–1.21 | 1.70 × 10−1 |
Brown | 866 | 0.10 | 3.15 × 10−2 | 1.36 | 0.97–1.92 | 7.68 × 10−2 | 2.11 × 10−1 | 2.11 | 1.22–3.64 | 7.57 × 10−3 |
Red | 108 | 0.11 | 2.12 × 10−2 | 1.33 | 0.94–1.87 | 1.03 × 10−1 | 2.27 × 10−1 | 1.12 | 0.58–2.14 | 7.36 × 10−1 |
Green-yellow | 44 | −0.03 | 5.29 × 10−1 | 0.84 | 0.61–1.16 | 2.84 × 10−1 | 3.90 × 10−1 | 1.27 | 0.70–2.29 | 4.35 × 10−1 |
Blue | 369 | 0.04 | 4.32 × 10−1 | 0.93 | 0.66–1.32 | 6.99 × 10−1 | 7.69 × 10−1 | 1.56 | 0.80–3.01 | 1.89 × 10−1 |
Pink | 52 | 0.03 | 5.91 × 10−1 | 0.65 | 0.47–0.91 | 1.08 × 10−2 | 3.97 × 10−2 | 1.35 | 0.72–2.53 | 3.50 × 10−1 |