Fig. 2

The annotation of chromatin states for TCF7L2-omics data. a The correlation with other genomic features, the distribution of each state bins as well as the average of gene expression for each of 18 states. The average gene expression is normalized by z-score and % total bin shows the percentage of each state in the human genome. b The biological interpretations of the HMM states and identification of four TCF7L2-assoicated States according to the emission probability and other genomic information. c The distribution of four TF-associated States on the gene structure. All genes’ length is normalized, representing the 5’–3’ region as gene body region and extending 90 kb of up/down steam for gene surrounding distribution. d Summary of bin distribution of three TCF7L2-associated states in five cancer cell types