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Fig. 2 | BMC Genomics

Fig. 2

From: Pan-cancer analysis reveals technical artifacts in TCGA germline variant calls

Fig. 2

WGA increases LOF variant burden. a LOF variant burden includes both SNV and indels. Red line indicates expected LOF burden from ExAC (155). b Individual LOF variant burden in cancers with WGA samples plotted by WGA status..* = Wilcoxon rank sum test p < 0.05, ** = Wilcoxon rank sum test p < 0.001. c Individual LOF variant burden in n = 13 samples that have both DNA and WGA samples available. ** = Wilcoxon paired rank sum test p < 0.001

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