Table 3 Average type 1 error rates of the statistic for testing interaction between two genes with marginal effects at two genes over 10 pairs of genes
From: Functional regression method for whole genome eQTL epistasis analysis with sequencing data
| Â | Rare Variants | Common & Rare Variants | ||||
|---|---|---|---|---|---|---|
Sample Size | 0.05 | 0.01 | 0.001 | 0.05 | 0.01 | 0.001 |
1000 | 0.0501 | 0.0108 | 0.0011 | 0.0486 | 0.0103 | 0.0010 |
2000 | 0.0493 | 0.0098 | 0.0010 | 0.0495 | 0.0101 | 0.0010 |
3000 | 0.0499 | 0.0095 | 0.0011 | 0.0497 | 0.0101 | 0.0011 |
4000 | 0.0494 | 0.0099 | 0.0010 | 0.0496 | 0.0096 | 0.0008 |
5000 | 0.0489 | 0.0097 | 0.0011 | 0.0497 | 0.0107 | 0.0010 |