A comprehensive proteogenomic study of the human Brucella vaccine strain 104 M

BMC Genomics

Table 1 The virulence factors and known protective antigens of B. abortus 104 M identified in this study

Function Group	Protein Accessions	Name	Description	Protein Length	Identified Peptides
Virulence factors	A0A0M5MHD4	Cgs	Cyclic β-1,2-glucan synthase	2867	135
	A0A0M4TBI0	Gmd	GDP-mannose 4,6-dehydratase	362	46
	A0A0M4SH46	Pgm	Phosphoglucomutase	543	36
	A0A0M3UZI1	BvrR	Transcriptional regulator	239	23
	A0A0M5MBG4	Per	Perosamine synthetase	367	19
	A0A0M3UYN6	Wzt	Teichoic acid ABC transporter ATPase	252	16
	A0A0M4SAL4	WbkC	GDP-mannose 4,6-dehydratase	259	14
	A0A0M4TBJ0	ManAoAg	Mannose-6-phosphate isomerase	390	11
	A0A0M5MBI2	ManCoAg	Mannose-1-phosphate guanyltransferase	474	10
	A0A0M5MCJ0	BvrS	Histidine kinase	601	8
	A0A0M4S2A5	WbkA	Glycosyl transferase family	372	6
	A0A0M5MH13	RicA	Acetyltransferase	175	5
	A0A0M4TDU8	VirB8	Conjugal transfer protein	239	3
	A0A0M4SA70	BtpA	Molecular chaperone	275	2
Protective antigens	A0A0M4SJF6	DnaK	Molecular chaperone DnaK	637	110
	A0A0M4TBF8		Trigger factor	485	77
	A0A0M5MBQ0	CobB	Cobyrinic acid a,c-diamide synthase	436	15
	A0A0M4TD92	GapA	Glyceraldehyde-3-phosphate dehydrogenase	335	81
	A0A0M4S0A3	SurA	Molecular chaperone SurA	318	17
	A0A0M4S1G5	OmpA	Membrane protein	261	13
	A0A0M4SJ84	Bp26	Membrane protein	250	9
	A0A0M4SZK3	Omp25	Membrane protein	213	22
	A0A0M4SCZ0	DnaJ	Molecular chaperone DnaJ	377	20
	A0A0M4S9R8	SodC	Superoxide dismutase	173	47
	A0A0M3UYK8		Invasion protein	173	32
	A0A0M4SDF8	Omp19	Membrane protein	177	13
	A0A0M4TD78	Omp16	Membrane protein	168	17
	A0A0M3V026	Ferritin	Bacterioferritin	161	9
	A0A0M4T393	RibE	Riboflavin synthase subunit beta	158	11
	A0A0M4TCK8	L7/L12	50S ribosomal protein	124	38
	A0A0M4SID4	AsnC	ArsR family transcriptional regulator	159	25

ISSN: 1471-2164