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Fig. 1 | BMC Genomics

Fig. 1

From: Gene dispersion is the key determinant of the read count bias in differential expression analysis of RNA-seq data

Fig. 1

a Distributions of signal-to-noise ratio (SNR) against read count. Read count bias was compared between two technical (MAQC-2 and Marioni dataset) and two unrelated (TCGA BRCA and KIRC dataset) replicate datasets. For a fair comparison regarding the replicate number and sequencing depth, TCGA BRCA and KIRC data were down-sampled and down-replicated to the Marioni dataset level (third column figures) from the original datasets (second column figures). b The likelihood ratio test statistic instead of the SNR was also plotted only for the significant genes

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BMC Genomics

ISSN: 1471-2164

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