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Table 1 The 16 public RNA-seq data tested

From: Gene dispersion is the key determinant of the read count bias in differential expression analysis of RNA-seq data

Name Experiment Test group size Control group size Replicate type
Marioni [9] Human liver vs. kidney 7 7 Technical
MAQC-2 [41] HBRR vs. SUHRR 7 7 Technical
Oliver [42] Head tissue of male vs. female Drosophila melanogaster 10 10 Technical
Barutcu [32] MCF7 vs. MCF10A 3 3 GI
Liu [33] 10nM E2-treated vs. control MCF7 7 7 GI
Li [34] Androgen-treated vs. control LNCaP cell line 4 3 GI
TCGA KIRC [27] Human renal clear cell carcinoma vs. matched normal tissue 7 7 Unrelated
TCGA BRCA [43] Human invasive breast cancer vs. matched normal tissue 7 7 Unrelated
TCGA PRAD [43] Human prostate adenocarcinoma vs. matched normal tissue 15 15 Unrelated
Tuch [44] Human oral squamous cell carcinoma vs. matched normal tissue 3 3 Unrelated
ModencodeFly [37] L1 Larvae vs. Embryos (12–14 h) 4 5 Technical
White pre-pupae (12 h) vs. L1 Larvae 5 4 Technical
Adult male (1 day) vs. White pre-pupae (12 h) 5 5 Technical
Pooled Larvae vs. pooled embryos (12–24 h) 6 6 Unrelated
Pooled pupae vs. pooled larvae 6 6 Unrelated
Pooled adult male vs. pooled pupae 3 6 Unrelated
  1. Abbreviation: GI genetically identical, HBRR Ambion First Choice Human Brain Reference RNA, SUHRR Stratagene Universal Human Reference RNA