Table 1 Positions of miR-619-5p binding sites and disease or function of target genes
From: The Binding Sites of miR-619-5p in the mRNAs of Human and Orthologous Genes
Gene | Site, nt | Disease or function | PMID | Gene | Site, nt | Disease or function | PMID |
|---|---|---|---|---|---|---|---|
ACSL6 | 4639 | prostate cancer | 19064571 | MRPS25 | 1609 | uncharacterized | 26302410 |
ADAL | 2041 | proliferation | 23645737 | MSH3 | 4139 | carcinogenesis | 24934723 |
ADAM17 | 3466 | breast cancer | 22967992 | NANOS1 | 3219 | retinoblastoma | 25100735 |
AGMAT | 2207 | renal carcinoma | 14648699 | NCMAP | 2259 | uncharacterized | |
AK1 | 1449 | hypertension | 23863634 | NDUFAF7 | 1697 | leukemia | 24292274 |
AKT2 | 4571 | neuroblastoma | 23468863 | NDUFC2 | 1646 | colon cancer | 25804238 |
ALDH3A2 | 2617 | detoxification | 9829906 | NLN | 4215 | Parkinson’s D. | 25378390 |
ANKRD16 | 2165 | breast cancer | 20453838 | NRIP2 | 2075 | atopic asthma | 17075290 |
AP5B1 | 4316 | differentiation | 15146197 | NSL1 | 3063 | kinetochore-protein | 16585270 |
ARGFX | 2642 | development | 20565723 | NXPE3 | 7447 | hepatocarcinoma | 26883180 |
ARHGEF39 | 1307 | tumorogenesis | 22327280 | OPTN | 2332 | glaucoma | 26302410 |
ARL11 | 1033 | tumorogenesis | 18337727 | PAG1 | 8156 | prostatic cancer | 21092590 |
ATCAY | 2991 | schizophrenia | 19165527 | PAQR5 | 4439 | ovarian cancer | 21761364 |
ATP1A2 | 4410 | tumorogenesis | 23474907 | PARK2 | 3729 | Parkinson’s D. | 26860075 |
BCL2L15 | 2650 | apoptosis | 16690252 | PBLD | 2077 | hepatocarcinoma | 26594798 |
BPNT1 | 1128 | ovarian cancer | 20628624 | PCGF5 | 5089 | Alzheimer’s D. | 16385451 |
C15orf40 | 523 | uncharacterized | PCSK5 | 8613 | tumorogenesis | 21094132 | |
C17orf75 | 2895 | uncharacterized | PDAP1 | 1926 | proliferation | 23555679 | |
C17orf75 | 3672 | PDCD4 | 3221 | tumorogenesis | 26871813 | ||
C21orf58 | 2668 | uncharacterized | 11707072 | PEX2 | 3056 | cerebellar ataxia | 21392394 |
C4orf19 | 2068 | uncharacterized | PGPEP1 | 1476 | liver cirrhosis | 25687677 | |
C6orf170 | 4113 | uncharacterized | 20159594 | PIK3R2 | 3345 | tumorogenesis | 26677064 |
C8orf44 | 336** | uncharacterized | PNPLA1 | 1991 | childhood obesity | 19390624 | |
C8orf44 | 1626 | PODNL1 | 1876 | uncharacterized | 12477932 | ||
C9orf85 | 871 | uncharacterized | POFUT1 | 4679 | hepatocarcinoma | 27003260 | |
CACNB2 | 4301 | hypertension | 25966706 | POLH | 5550 | ovarian cancer | 25831546 |
CACNG8 | 3218 | cardiomyopathy | 26710323 | PPM1K | 2192 | diabetes mellitus | 23446828 |
CACNG8 | 5006 | PPP1R12B | 5156 | childhood asthma | 23640410 | ||
CACNG8 | 7535 | PRRG4 | 998 | Parkinson’s D | 19772629 | ||
CALHM1 | 2896 | Alzheimer’s D. | 26944452 | PSMB2 | 2925 | proteolysis | 21660142 |
CCBE1 | 3321 | ovarian cancer | 19935792 | PTCD3 | 4116 | osteosarcoma | 19427859 |
CCDC114 | 261* | dyskinesia | 23506398 | PTK6 | 2233 | tumorogenesis | 27311570 |
CD109 | 6841 | bladder cancer | 20946523 | QRFPR | 1949 | metabolic S. | 16648250 |
CD36 | 4042 | atherosclerosis | 16515687 | RAB11FIP1 | 4928 | cell transport | 26790954 |
CD68 | 1398 | carcinomas | 21113139 | RAB3IP | 3975 | tumorogenesis | 12007189 |
CDAN1 | 4296 | erythropoiesis | 19336738 | 7022 | |||
CDHR3 | 4878 | asthma | 25848009 | RAB7L1 | 1693 | Parkinson’s D. | 26914237 |
CEP68 | 4394 | cervical cancer | 17570516 | RBBP9 | 1818 | tumorogenesis | 21933118 |
CHST5 | 2946 | colon carcinoma | 12107080 | RGS3 | 205* | cardiovascular D. | 24375609 |
CHST6 | 2979 | dystrophy | 20539220 | RPS6KA6 | 7136 | tumorogenesis | 26732474 |
CHST6 | 3876 | SCN11A | 5871 | neurophaty | 25791876 | ||
CIAO1 | 2416 | tumorogenesis | 9556563 | SEPT11 | 4033 | hepatocarcinoma | 20419844 |
CIAO1 | 3814 | SEPT14 | 1575 | Parkinson’s D | 27115672 | ||
CLEC19A | 1747 | lectin | 12975309 | SGTB | 3142 | lymphopoesis | 2158125 |
CLTC | 7006 | pancreatic cancer | 23228632 | SH3GLB1 | 4856 | prostate cancer | 27748942 |
CORO2A | 2227 | colon cancer | 23490283 | SLC15A2 | 4333 | hepatocarcinoma | 25965825 |
COX18 | 1264 | tumorogenesis | 20819778 | SLC17A5 | 2389 | cardiovascular D | 27872510 |
CPM | 2698 | renal carcinoma | 23172796 | SLC26A2 | 5066 | colorectal cancer | 23840040 |
CPM | 4996 | SLC26A4 | 4210 | hearing loss | 27729126 | ||
CPT2 | 2557 | sudden death | 21641254 | SLC28A2 | 2196 | chronic hepatitis C | 23195617 |
CYB5RL | 3426 | transcription | 16344560 | SLC7A11 | 6304 | tumorogenesis | 26729415 |
CYP20A1 | 2539 | tumorogenesis | 15191668 | SLC7A14 | 8487 | breast cancer | 20379614 |
CYP20A1 | 4709 | SNX22 | 902 | liver-disease | 21988832 | ||
CYP27C1 | 3823 | self-rated health | 20707712 | SOWAHC | 3417 | retrotransposon | 22234889 |
CYP2W1 | 2176 | colorectal cancer | 22993331 | SPATA13 | 5020 | colorectal cancer | 17599059 |
DAP3 | 1842 | breast cancer | 22287761 | SPATA5 | 5648 | microcephaly | 26299366 |
DCAF10 | 3305 | lung cancer | 28336923 | SPATS2 | 3332 | breast cancer | 20379614 |
DCAF10 | 4559 | SPN | 5287 | tumorogenesis | 25551301 | ||
DCLRE1C | 2966 | Omenn syndrome | 25981738 | STAC2 | 2241 | inherited ataxias | 16713569 |
DDOST | 1782 | hyperglycemia | 22305527 | SYNJ2BP | 1298 | breast cancer | 19349195 |
DHODH | 1709 | melanoma | 21430780 | SYNJ2BP | 4175 | ||
DHRS9 | 1281* | tumorogenesis | 26254099 | TCEB1 | 1964 | tumorogenesis | 23083832 |
DNAL1 | 4925 | dyskinesia | 15845866 | TIGD6 | 3439 | uncharacterized | |
DSCR6 | 1706 | Down syndrome | 10814524 | TMEM156 | 1593 | uncharacterized | |
ERBB3 | 5104 | tumorogenesis | 26689995 | TMEM19 | 3510 | uncharacterized | |
FADS6 | 1777 | liver disease | 21988832, | TMEM213 | 875 | uncharacterized | |
FAM161A | 2785 | retinal disease | 25749990 | TMEM214 | 1190 | uncharacterized | |
FAM227A | 4981 | cancer | 26759717 | TMEM50B | 1026 | uncharacterized | |
FAM84B | 3626 | tumorogenesis | 25980316 | TMEM56 | 1243 | nicotine dependence | 20379614 |
FBLIM1 | 2126 | breast cancer, | 23645746 | TMF1 | 4736 | prostate cancer | 19330832 |
FBXL22 | 1411 | cardiomyopathy | 24324551 | TMOD2 | 7816 | bladder cancer | 15095301 |
FBXO27 | 1535 | leukemia | 126433 | TNFRSF10A | 1621 | cancer | 27780136 |
FGD4 | 7619 | cancer | 22589722 | TNFRSF10D | 1532 | cancer | 26542757 |
FKBP14 | 1515 | ovarian cancer | 27931282 | TOP3A | 3814 | leukaemia | 22050635 |
FKBP14 | 2129 | TPRG1L | 1754 | uncharacterized | |||
FKBP5 | 7114 | schizophrenia | 25522420 | TRIM72 | 1885 | ischemia | 26790476 |
FXN | 3288 | metabolic disease | 26717909 | TRPM7 | 8079 | neuroblastoma | 27402209 |
GDPD1 | 1559 | phosphodiesterase | 18991142 | TRPM7 | 8221 | carcinoma | 26779625 |
GEMIN8 | 2172 | neuropathy | 16434402 | TXNDC15 | 2460 | thrombosis | 21642008 |
GGT6 | 1956 | ovarian cancer | 25356737 | TYW5 | 3692 | schizophrenia | 23974872 |
GK5 | 3808 | glioblastoma | 25936394 | UACA | 6120 | lung cancer | 22407486 |
GK5 | 6355 | glioblastoma | 25936394 | UACA | 6120 | thyroid diseases | 15358194 |
GLB1L | 2224 | phosphatase | 21382349 | UBIAD1 | 2881 | cancer | 23759948 |
GOLGA3 | 7240 | immune disease | 17711851 | UBXN2A | 1665 | colon cancer | 24625977 |
GP2 | 1877 | crohn disease | 22891285 | UPK1B | 1513 | cancer | 16354592, |
GPR65 | 3309 | tumorogenesis | 24152439 | UQCRB | 1269 | colorectal cancer | 22545919 |
GPR65 | 3309 | immune diseases | 15665078 | USP29 | 2* | protease | 10958632 |
GPR82 | 2664 | uncharacterized | VHL | 3764 | tumorogenesis | 27460078 | |
GPRIN2 | 6676 | schizophrenia | 27244233 | VHL | 3898 | ||
GTPBP10 | 1873 | prostate cancer | 27409348 | VWA2 | 3366 | colon cancer | 15580307 |
H6PD | 5754 | tumorogenesis | 15221007 | WDR73 | 1736 | microcephaly | 25466283 |
HM13 | 1745 | glioblastoma | 28198167 | XIAP | 5681 | ovarian cancer | 26779627 |
IFIT3 | 1864 | pancreatic cancer | 25650658 | YAE1D1 | 1548 | oral cancer | 23318452 |
ISY1 | 686** | uncharacterized | ZBTB24 | 4842 | hepatocarcinoma | 27730394 | |
IYD | 1658 | hypothyroidism. | 18765512 | ZC3H12D | 2812 | Acute lung injury | 26059755 |
KIAA1456 | 2536 | colorectal cancer | 24743840 | ZDHHC20 | 3390 | tumorogenesis | 20334580 |
KIF11 | 3598 | tumorogenesis | 28011472 | ZFP30 | 3463 | hypertension | 19851296 |
KLHL23 | 2570 | tumorogenesis | 23676014 | ZNF114 | 1827 | transcription factor | 8467795 |
KPNA1 | 5711 | breast cancer | 26052702 | ZNF197 | 3446 | thyroid cancer | 12682018 |
KREMEN1 | 2199 | schizophrenia | 20153141 | ZNF320 | 5534 | glioblastoma | 11536051 |
KREMEN1 | 2792 | schizophrenia | 20153141 | ZNF429 | 2081** | transcription factor | 7865130 |
LAX1 | 2057 | uncharacterized | ZNF445 | 8820 | transcription factor | 16368201 | |
LILRA6 | 2201 | tumorogenesis | 26769854 | ZNF461 | 3087 | transcription factor | 15004467 |
LIMD1 | 5735 | breast cancer | 27656835 | ZNF549 | 3736 | transcription factor | 16344560 |
LIMS1 | 3931 | cancer | 27590440 | ZNF557 | 4791 | transcription factor | 15851553 |
LMOD3 | 3224 | myopathy | 25250574 | ZNF626 | 4620 | liver diseases | 18255255 |
LMOD3 | 3993 | Alzheimer’s D | 22881374 | ZNF667 | 3240 | transcription factor | 17397802 |
METTL6 | 1188 | breast cancer | 25151356 | ZNF716 | 2799 | cardiovascular D | 24376456 |
MR1 | 3664 | hepatocarcinoma | 26823810 | ZNF780B | 5415 | transcription factor | 15057824 |
MREG | 1540 | pulmonary D | 20463177 | ZNF84 | 4920 | transcription factor | 11856868 |
ZNF841 | 3422 | transcription factor | 24280104 |