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Table 1 Functions of overall differentially expressed genes

From: Gene expression and adaptive noncoding changes during human evolution

Set Collection # genes r_rb SE(r_rb)
chr17q11 C1:All 66 0.88 0.021
chr12q13 C1:All 152 0.84 0.026
NIKOLSKY BREAST CANCER 17Q11 Q21 AMPLICON C2:CGP 80 0.84 0.033
chr17q21 C1:All 164 0.69 0.033
chr4q21 C1:All 61 0.62 0.066
chr1p13 C1:All 79 0.59 0.06
GNF2 DNM1 C4:CGN 63 0.41 0.046
RICKMAN HEAD AND NECK CANCER A C2:CGP 77 0.34 0.06
LEIN NEURON MARKERS C2:CGP 50 0.34 0.052
CAHOY NEURONAL C6:All 84 0.33 0.053
GCM MAP1B C4:CGN 53 0.33 0.076
ANASTASSIOU CANCER MESENCHYMAL TRANSITION SIGNATURE C2:CGP 53 0.33 0.069
SABATES COLORECTAL ADENOMA UP C2:CGP 86 0.33 0.049
GNF2 CCNA2 C4:CGN 52 0.32 0.065
KRAS.KIDNEY UP.V1 UP C6:All 113 0.32 0.047
VOLTAGE GATED CATION CHANNEL ACTIVITY C5:MF 57 0.31 0.061
NAKAYAMA SOFT TISSUE TUMORS PCA2 UP C2:CGP 71 0.31 0.053
GCM MAPK10 C4:CGN 71 0.31 0.059
CERVERA SDHB TARGETS 1 UP C2:CGP 95 0.3 0.052
VOLTAGE GATED CHANNEL ACTIVITY C5:MF 63 0.3 0.058
  1. The 20 (of 5247) MSigDB gene sets most enriched with genes scoring high for overall differential expression between humans and chimpanzees are listed. Collection is the MSigDB collection containing the set (one of 16). genes is the number of genes whose expression we measured in the set (at least 50). r rb is the rank-biserial correlation between scores for differential expression and membership in the set; sets are ordered by decreasing r rb. SE(r rb) is the standard error of r rb via bootstrapping with 10,000 replicates