Fine-mapping host genetic variation underlying outcomes to Mycobacterium bovis infection in dairy cows

BMC Genomics

Table 1 Genomic regions associated with bTB resistance

	chr	Position (bp)	LRT	h ² _r	Candidate Genes
NVLs	100-SNP windows
	17	19,342,437–19,650,334	15.10	0.053	LOC783390 matrin 3 pseudogene
	22	57,159,725–57,547,638	17.42	0.039	RAF1, MKRN2, MKRN2OS, TSEN2, PPARG, MIR2373
	23	6,603,103–7,066,824	20.05	0.035	LRRC1, LOC104975626, KLHL31, GCLC, DSB, BOLA-DYA, BOLA-DYB, BOLA-DOB, LOC100140517
	30-SNP windows
	22	57,311,814–57,451,910	16.87	0.026	TSEN2, PPARG
	22	57,396,014–57,510,400	17.61	0.025	PPARG, MIR2373
	23	6,669,083–6,873,884	20.00	0.041	LOC104975626, KLHL31
	23	6,774,875–6,975,825	16.64	0.046	KLHL31, GCLC, DSB
Cases	100-SNP windows
	23	6,411,854–6,774,223	15.12	0.033	MLIP, LRRC1, LOC104975626, KLHL31

For the associated trait, the table shows chromosome, start and end position of genomic window in base pairs, LRT, heritability of the region and candidate genes residing within the window of significance. Genomic regions at both the genome-wide and suggestive level identified by regional heritability mapping using 100- and 30-SNP window size are presented

ISSN: 1471-2164