Genome wide association study and genomic prediction for fatty acid composition in Chinese Simmental beef cattle using high density SNP array

Zhu, Bo; Niu, Hong; Zhang, Wengang; Wang, Zezhao; Liang, Yonghu; Guan, Long; Guo, Peng; Chen, Yan; Zhang, Lupei; Guo, Yong; Ni, Heming; Gao, Xue; Gao, Huijiang; Xu, Lingyang; Li, Junya

doi:10.1186/s12864-017-3847-7

Table 2 Genomic regions associated with the saturated fatty acids in Chinese Simmental cattle using BayesB method

From: Genome wide association study and genomic prediction for fatty acid composition in Chinese Simmental beef cattle using high density SNP array

FA Trait	Chr	Associated Window	nSNP	rs_ID_start	rs_ID_end	Genetic variance for 100 kb window	Positional/putative candidate gene	Gene name
C14:0	chr25	15100001:15200000	37	rs134854144	rs136080067	0.014154507
	chr23	25100001:25200000	47	rs132630789	rs109109903	0.014619034	ELOVL5	Bos taurus Elongation of very long chain fatty acids protein 5
	chr22	59100001:59200000	47	rs41638475	rs109645438	0.074590648	HDAC11 NUP210	Bos taurus histone deacetylase 11 Bos taurus nucleoporin 210
	chr19	51300001:51400000	22	rs41921222	rs41919992	0.100435511	FASN	Bos taurus fatty acid synthase
C18:0	chr6	104300001:104400000	37	rs43482940	rs134151071	0.011996761	DMP1	Bos taurus dentin matrix acidic phosphoprotein 1
	chr6	70900001:71000000	33	rs108998288	rs137260120	0.012677451
	chr6	41100001:41200000	19	rs134035533	rs43461220	0.018256368	SLIT2	Bos taurus slit guidance ligand 2
C20:0	chr2	11700001:11800000	31	rs134430461	rs109568935	0.028998035
	chr4	107500001:107600000	23	rs132935788	rs135713587	0.012116165	CASP2 CLCN1 FAM131B ZYX	Bos taurus caspase 2, apoptosis-related cysteine peptidase Bos taurus chloride voltage-gated channel 1 Bos taurus family with sequence similarity 131 member B Bos taurus zyxin
	chr6	24100001:24200000	20	rs110959363	rs110137781	0.018578393
	chr7	111100001:111200000	31	rs133722129	rs43539829	0.013985525	PJA2	Bos taurus praja ring finger 2, E3 ubiquitin protein ligase
	chr12	13800001:13900000	36	rs132809847	rs109642481	0.012955962
	chr12	71200001:71300000	2	rs137175740	rs42873431	0.022999321
	chr14	35500001:35600000	24	rs136365597	rs137334521	0.062770091
	chr15	47400001:47500000	16	rs42670335	rs41772249	0.032833294	FAM160A2	Bos taurus family with sequence similarity 160 member A2
	chr23	11400001:11500000	16	rs133114050	rs110729743	0.015925179

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ISSN: 1471-2164

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