Skip to main content

Table 3 Correlation between DMGs and DEGs

From: Genome-wide analysis of DNA methylation in hypothalamus and ovary of Capra hircus

  Hypothalamus Obs. DMGs Obs. DEGs DEGs ∩ DMGs 100 k simulation of ∩ ±SD P-value
Positive Correlation Hyper DMGs/over DEGs 455 1138 34 30.46 5.25 0.318
Hypo DMGs/under DEGs 1263 1583 42 103.44 9.38 1.97E-10
Negative Correlation Hyper DMGs/under DEGs 455 1583 49 34.89 5.60 0.0167
Hypo DMGs/over DEGs 1263 1138 231 99.10 9.11 1.29E-46
  1. Hypo and hyper-methylated genes (FDR < 0.05) overlapping with under and overexpressed genes (FDR < 0.001) in the hypothalamus (DEGs ∩ DMGs). A jackknife simulation test with relative P-values (observed vs random expectation) was performed for each subgroup