Fig. 2
From: Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice
Cardiac Transcriptome in Nrf2 Knockout Mice: a Hierarchal clustering of 152 differentially expressed genes (DEGs) in Nrf2 KO hearts uncovered by RNA sequencing (RNAseq) (n = 3–4/group). b 129 DEGs were downregulated while only 23 were upregulated. c DEGs separated by log2 fold change (FC) showed that most DEGs yielded a log2 FC less than 1.0 (84%). Apart from Nrf2 itself, just 22 (15%) and 2 (1%) DEGs revealed a log2 FC greater than 1.0 and 2.0, respectively. d-e Real-time quantitative PCR (n = 4–6/group) of 8 DEGs shows a strong correlation with RNAseq log2FC. *p < 0.05, **p < 0.01, ***p < 0.001