Fig. 3

Species-mixing experiment. Single-cell expression data from one-to-one cell mixture of human K562 and mouse 3T3 cells, together with single-cell data from cell suspensions of 3T3 cells and K562 cells alone. Data were mapped independently to the human and mouse genome. Reads mapping to both genomes with ≤3 mismatches were excluded. For the one-to-one mixture, 247 cells and 243 cells were classified as human and mouse, respectively, 6 cells were classified as cross-species cell multiplets