Fig. 11
From: Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible
Cartoon description of RepProfile probability distribution. a There are many repeat copies in the genome. Each has some probability of being hyper-edited. H tells us which are hyper-edited and which are not. b Within each repeat, each position has a chance of being a SNP and each A in a hyper-edited repeat has a chance of being edited. T indicates which positions are SNPs and which are edited. c Any base can be sequenced at any position. G gives the distribution over A/C/G/T at each position. d Each repeat has a probability of generating the next read (defined by X), and A is the specific aligned position for the read. The read bases, R, are drawn from the corresponding distributions in G