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Table 1 Sensitivity and PPV for RepProfile and competing methods in the three different simulations

From: Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible

Exact Rep Sens. PPV
 RepProfile 0.94 0.99
 Porath 0.07 1.0
 EER uniq 0.36 0.99
 EER +rep 0.90 0.14
Clone
 RepProfile 0.95 1.0
 Porath 0.13 0.97
 EER uniq 0.55 0.82
 EER +rep 0.91 0.42
Random
 RepProfile 0.87 0.99
 Porath 0.50 0.98
 EER uniq 0.70 0.98
 EER +rep 0.86 0.74
  1. Top: Simulation from 24 identical copies of a hypothetical repeat. Middle: Simulation of editing predicted by clones. Bottom: Random hyper-editing of FB4_DM