TY - STD
TI - Schwartz, E. and T. Lachish, Artemisinin-based combination therapy (ACT) versus atovaquone-proguanil: do not choose between but, rather, combine them. Evidence Based Medicine, 2016. 21(2): p. 64–64.
ID - ref1
ER -
TY - JOUR
AU - Olliaro, P. L.
AU - Taylor, W. R.
PY - 2004
DA - 2004//
TI - Developing artemisinin based drug combinations for the treatment of drug resistant falciparum malaria: a review
JO - J Postgrad Med
VL - 50
ID - Olliaro2004
ER -
TY - JOUR
AU - Eastman, R. T.
AU - Fidock, D. A.
PY - 2009
DA - 2009//
TI - Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
JO - Nat Rev Microbiol
VL - 7
ID - Eastman2009
ER -
TY - JOUR
AU - Chakraborty, A.
PY - 2016
DA - 2016//
TI - Emerging drug resistance in plasmodium falciparum: a review of well-characterized drug targets for novel antimalarial chemotherapy
JO - Asian Pac J of Tro Dis
VL - 6
UR - https://doi.org/10.1016/S2222-1808(16)61090-3
DO - 10.1016/S2222-1808(16)61090-3
ID - Chakraborty2016
ER -
TY - JOUR
AU - Cowman, A. F.
PY - 2016
DA - 2016//
TI - Malaria: biology and disease
JO - Cell
VL - 167
UR - https://doi.org/10.1016/j.cell.2016.07.055
DO - 10.1016/j.cell.2016.07.055
ID - Cowman2016
ER -
TY - JOUR
AU - Plowe, C. V.
PY - 2007
DA - 2007//
TI - World antimalarial resistance network (WARN) III: molecular markers for drug resistant malaria
JO - Malar J
VL - 6
UR - https://doi.org/10.1186/1475-2875-6-121
DO - 10.1186/1475-2875-6-121
ID - Plowe2007
ER -
TY - STD
TI - Sidhu AB, Verdier-Pinard D, Fidock DA. Chloroquine resistance in plasmodium falciparum malaria parasites conferred by pfcrt mutations. Science. 2002;298
ID - ref7
ER -
TY - JOUR
AU - Guler, J. L.
PY - 2015
DA - 2015//
TI - Atovaquone tolerance in plasmodium falciparum parasites selected for high-level resistance to a dihydroorotate dehydrogenase inhibitor
JO - Antimicrob Agents Chemother
VL - 59
UR - https://doi.org/10.1128/AAC.02347-14
DO - 10.1128/AAC.02347-14
ID - Guler2015
ER -
TY - STD
TI - Herman JD, et al. A genomic and evolutionary approach reveals non-genetic drug resistance in malaria. Genome Biol. 2014;15(11):511.
ID - ref9
ER -
TY - STD
TI - Gabryszewski, S.J., et al., Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology. PLOS Pathog, 2016. 12(11): p. e1005976.
ID - ref10
ER -
TY - STD
TI - Meylan S, et al. Carbon sources tune antibiotic susceptibility in Pseudomonas Aeruginosa via tricarboxylic acid cycle control. Cell Chem Biol. 2017; 24:195-206.
ID - ref11
ER -
TY - JOUR
AU - El-Halfawy, O. M.
AU - Valvano, M. A.
PY - 2012
DA - 2012//
TI - Non-genetic mechanisms communicating antibiotic resistance: rethinking strategies for antimicrobial drug design
JO - Expert Opin Drug Discov
VL - 7
UR - https://doi.org/10.1517/17460441.2012.712512
DO - 10.1517/17460441.2012.712512
ID - El-Halfawy2012
ER -
TY - JOUR
AU - Ashley, E. A.
PY - 2014
DA - 2014//
TI - Spread of artemisinin resistance in plasmodium falciparum malaria
JO - N Engl J Med
VL - 371
UR - https://doi.org/10.1056/NEJMoa1314981
DO - 10.1056/NEJMoa1314981
ID - Ashley2014
ER -
TY - JOUR
AU - Miotto, O.
PY - 2015
DA - 2015//
TI - Genetic architecture of artemisinin-resistant plasmodium falciparum
JO - Nat Genet
VL - 47
UR - https://doi.org/10.1038/ng.3189
DO - 10.1038/ng.3189
ID - Miotto2015
ER -
TY - JOUR
AU - Straimer, J.
PY - 2015
DA - 2015//
TI - K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates
JO - Science
VL - 347
UR - https://doi.org/10.1126/science.1260867
DO - 10.1126/science.1260867
ID - Straimer2015
ER -
TY - JOUR
AU - Ariey, F.
PY - 2014
DA - 2014//
TI - A molecular marker of artemisinin-resistant plasmodium falciparum malaria
JO - Nature
VL - 505
UR - https://doi.org/10.1038/nature12876
DO - 10.1038/nature12876
ID - Ariey2014
ER -
TY - JOUR
AU - Brown, T. S.
PY - 2015
DA - 2015//
TI - Plasmodium falciparum field isolates from areas of repeated emergence of drug resistant malaria show no evidence of hypermutator phenotype
JO - Infection, Genetics and Evolution: J Mol Epidemiol Evol Genet Infect Dis
VL - 30
UR - https://doi.org/10.1016/j.meegid.2014.12.010
DO - 10.1016/j.meegid.2014.12.010
ID - Brown2015
ER -
TY - JOUR
AU - Cheng, Q.
AU - Kyle, D. E.
AU - Gatton, M. L.
PY - 2012
DA - 2012//
TI - Artemisinin resistance in Plasmodium falciparum: A process linked to dormancy? International Journal for parasitology
JO - Drugs and Drug Resist
VL - 2
UR - https://doi.org/10.1016/j.ijpddr.2012.01.001
DO - 10.1016/j.ijpddr.2012.01.001
ID - Cheng2012
ER -
TY - STD
TI - Codd A, et al. Artemisinin-induced parasite dormancy: a plausible mechanism for treatment failure. Malar J. 2011;10
ID - ref19
ER -
TY - JOUR
AU - Straimer, J.
PY - 2015
DA - 2015//
TI - Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates
JO - Sci
VL - 347
UR - https://doi.org/10.1126/science.1260867
DO - 10.1126/science.1260867
ID - Straimer2015
ER -
TY - JOUR
AU - Mbengue, A.
PY - 2015
DA - 2015//
TI - A molecular mechanism of artemisinin resistance in plasmodium falciparum malaria
JO - Nat
VL - 520
UR - https://doi.org/10.1038/nature14412
DO - 10.1038/nature14412
ID - Mbengue2015
ER -
TY - JOUR
AU - Ying-Zi, Y.
AU - Little, B.
AU - Meshnick, S. R.
PY - 1994
DA - 1994//
TI - Alkylation of proteins by artemisinin: effects of heme, pH, and drug structure
JO - Biochem Pharmacol
VL - 48
UR - https://doi.org/10.1016/0006-2952(94)90287-9
DO - 10.1016/0006-2952(94)90287-9
ID - Ying-Zi1994
ER -
TY - JOUR
AU - Dalal, S.
AU - Klemba, M.
PY - 2015
DA - 2015//
TI - Amino acid efflux by asexual blood-stage plasmodium falciparum and its utility in interrogating the kinetics of hemoglobin endocytosis and catabolism in vivo
JO - Mol Biochem Parasitol
VL - 201
UR - https://doi.org/10.1016/j.molbiopara.2015.07.002
DO - 10.1016/j.molbiopara.2015.07.002
ID - Dalal2015
ER -
TY - JOUR
AU - Klonis, N.
PY - 2011
DA - 2011//
TI - Artemisinin activity against plasmodium falciparum requires hemoglobin uptake and digestion
JO - Proc Natl Acad Sci U S A
VL - 108
UR - https://doi.org/10.1073/pnas.1104063108
DO - 10.1073/pnas.1104063108
ID - Klonis2011
ER -
TY - STD
TI - Wang J, et al. Artemisinin Directly Targets Malarial Mitochondria through Its Specific Mitochondrial Activation. PLoS One. 2010;5(3):e9582.
ID - ref25
ER -
TY - JOUR
AU - Chen, N.
PY - 2014
DA - 2014//
TI - Fatty acid synthesis and pyruvate metabolism pathways remain active in Dihydroartemisinin-induced dormant ring stages of plasmodium falciparum
JO - Antimicrob Agents Chemother
VL - 58
UR - https://doi.org/10.1128/AAC.02647-14
DO - 10.1128/AAC.02647-14
ID - Chen2014
ER -
TY - STD
TI - Vega-Rodríguez J, et al. Implications of glutathione levels in the plasmodium berghei response to chloroquine and artemisinin. PLoS One. 2015;10(5):e0128212.
ID - ref27
ER -
TY - JOUR
AU - Cobbold, S. A.
PY - 2016
DA - 2016//
TI - Metabolic dysregulation induced in plasmodium falciparum by Dihydroartemisinin and other front-line antimalarial drugs
JO - J Infect Dis
VL - 213
UR - https://doi.org/10.1093/infdis/jiv372
DO - 10.1093/infdis/jiv372
ID - Cobbold2016
ER -
TY - JOUR
AU - Peatey, C. L.
PY - 2015
DA - 2015//
TI - Mitochondrial membrane potential in a small subset of artemisinin-induced dormant plasmodium falciparum parasites in vitro
JO - J Infect Dis
VL - 212
UR - https://doi.org/10.1093/infdis/jiv048
DO - 10.1093/infdis/jiv048
ID - Peatey2015
ER -
TY - JOUR
AU - Meshnick, S. R.
PY - 2002
DA - 2002//
TI - Artemisinin: mechanisms of action, resistance and toxicity
JO - Int J Parasitol
VL - 32
UR - https://doi.org/10.1016/S0020-7519(02)00194-7
DO - 10.1016/S0020-7519(02)00194-7
ID - Meshnick2002
ER -
TY - JOUR
AU - Eckstein-Ludwig, U.
PY - 2003
DA - 2003//
TI - Artemisinins target the SERCA of plasmodium falciparum
JO - Nature
VL - 424
UR - https://doi.org/10.1038/nature01813
DO - 10.1038/nature01813
ID - Eckstein-Ludwig2003
ER -
TY - JOUR
AU - Golenser, J.
PY - 2006
DA - 2006//
TI - Current perspectives on the mechanism of action of artemisinins
JO - Int J Parasitol
VL - 36
UR - https://doi.org/10.1016/j.ijpara.2006.07.011
DO - 10.1016/j.ijpara.2006.07.011
ID - Golenser2006
ER -
TY - JOUR
AU - Efferth, T.
AU - Oesch, F.
PY - 2004
DA - 2004//
TI - Oxidative stress response of tumor cells: microarray-based comparison between artemisinins and anthracyclines
JO - Biochem Pharmacol
VL - 68
UR - https://doi.org/10.1016/j.bcp.2004.03.003
DO - 10.1016/j.bcp.2004.03.003
ID - Efferth2004
ER -
TY - JOUR
AU - Antoine, T.
PY - 2014
DA - 2014//
TI - Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential
JO - J Antimicrob Chemother
VL - 69
UR - https://doi.org/10.1093/jac/dkt486
DO - 10.1093/jac/dkt486
ID - Antoine2014
ER -
TY - JOUR
AU - Sun, C.
PY - 2015
DA - 2015//
TI - Two distinct and competitive pathways confer the cellcidal actions of artemisinins
JO - Microbial Cell
VL - 2
UR - https://doi.org/10.15698/mic2015.01.181
DO - 10.15698/mic2015.01.181
ID - Sun2015
ER -
TY - STD
TI - Li, W., et al., Yeast model uncovers dual roles of mitochondria in the action of artemisinin. PLoS Genet, 2005. 1(3): p. e36.
ID - ref36
ER -
TY - JOUR
AU - Kamau, E.
PY - 2015
DA - 2015//
TI - K13-propeller polymorphisms in plasmodium falciparum parasites from sub-Saharan Africa
JO - J Infect Dis
VL - 211
ID - Kamau2015
ER -
TY - JOUR
AU - Isozumi, R.
PY - 2015
DA - 2015//
TI - Novel mutations in K13 propeller Gene of artemisinin-resistant plasmodium falciparum
JO - Emerg Infect Dis
VL - 21
UR - https://doi.org/10.3201/eid2103.140898
DO - 10.3201/eid2103.140898
ID - Isozumi2015
ER -
TY - JOUR
AU - Klonis, N.
PY - 2013
DA - 2013//
TI - Altered temporal response of malaria parasites determines differential sensitivity to artemisinin
JO - Proc Natl Acad Sci U S A
VL - 110
UR - https://doi.org/10.1073/pnas.1217452110
DO - 10.1073/pnas.1217452110
ID - Klonis2013
ER -
TY - STD
TI - Mok S, et al. Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription. BMC Genomics. 2011:12(1).
ID - ref40
ER -
TY - JOUR
AU - Teuscher, F.
PY - 2010
DA - 2010//
TI - Artemisinin-induced dormancy in plasmodium falciparum: duration, recovery rates, and implications in treatment failure
JO - J Infect Dis
VL - 202
UR - https://doi.org/10.1086/656476
DO - 10.1086/656476
ID - Teuscher2010
ER -
TY - JOUR
AU - Witkowski, B.
PY - 2010
DA - 2010//
TI - Increased tolerance to artemisinin in plasmodium falciparum is mediated by a quiescence mechanism
JO - Antimicrob Agents Chemother
VL - 54
UR - https://doi.org/10.1128/AAC.01636-09
DO - 10.1128/AAC.01636-09
ID - Witkowski2010
ER -
TY - STD
TI - Collaborativea TPGD, PlasmoDB: An integrative database of the Plasmodium falciparum genome. Tools for accessing and analyzing finished and unfinished sequence data. Nucleic Acids Res. 2001;29(1):66–9.
ID - ref43
ER -
TY - STD
TI - Fidock DA, et al. Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Mol Cell. 2000:6.
ID - ref44
ER -
TY - STD
TI - Peterson DS, Walliker D, Wellems TE. Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Proc Natl Acad Sci U S A. 1988;85(23):9114-9118.
ID - ref45
ER -
TY - JOUR
AU - Siregar, J. E.
PY - 2015
DA - 2015//
TI - Direct evidence for the atovaquone action on the plasmodium cytochrome bc1 complex
JO - Parasitol Int
VL - 64
UR - https://doi.org/10.1016/j.parint.2014.09.011
DO - 10.1016/j.parint.2014.09.011
ID - Siregar2015
ER -
TY - JOUR
AU - Phillips, M. A.
AU - Rathod, P. K.
PY - 2010
DA - 2010//
TI - Plasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy
JO - Infect Disord Drug Targets
VL - 10
UR - https://doi.org/10.2174/187152610791163336
DO - 10.2174/187152610791163336
ID - Phillips2010
ER -
TY - STD
TI - Fuhrer T, et al. Genomewide landscape of gene–metabolome associations in Escherichia coli. Mol Syst Biol. 2017;13(1):907.
ID - ref48
ER -
TY - JOUR
AU - Mok, S.
PY - 2015
DA - 2015//
TI - Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance
JO - Science
VL - 347
UR - https://doi.org/10.1126/science.1260403
DO - 10.1126/science.1260403
ID - Mok2015
ER -
TY - STD
TI - Plata G, et al. Reconstruction and flux-balance analysis of the plasmodium falciparum metabolic network. Mol Syst Biol. 2010;6
ID - ref50
ER -
TY - JOUR
AU - Painter, H. J.
PY - 2007
DA - 2007//
TI - Specific role of mitochondrial electron transport in blood-stage plasmodium falciparum
JO - Nature
VL - 446
UR - https://doi.org/10.1038/nature05572
DO - 10.1038/nature05572
ID - Painter2007
ER -
TY - STD
TI - Langer RC, Vinetz JM. Plasmodium ookinete-secreted chitinase and parasite penetration of the mosquito peritrophic matrix. Trends Parasitol. 2001;17(6):269–72.
ID - ref52
ER -
TY - JOUR
AU - Thiele, I.
AU - Palsson, B. O.
PY - 2010
DA - 2010//
TI - A protocol for generating a high-quality genome-scale metabolic reconstruction
JO - Nat Protocols
VL - 5
UR - https://doi.org/10.1038/nprot.2009.203
DO - 10.1038/nprot.2009.203
ID - Thiele2010
ER -
TY - JOUR
AU - Sturm, A.
PY - 2015
DA - 2015//
TI - Mitochondrial ATP synthase is dispensable in blood-stage plasmodium berghei rodent malaria but essential in the mosquito phase
JO - Proc Natl Acad Sci
VL - 112
UR - https://doi.org/10.1073/pnas.1423959112
DO - 10.1073/pnas.1423959112
ID - Sturm2015
ER -
TY - JOUR
AU - Ginsburg, H.
PY - 2002
DA - 2002//
TI - Abundant proton pumping in plasmodium, but why?
JO - Trends Parasitol
VL - 18
UR - https://doi.org/10.1016/S1471-4922(02)02350-4
DO - 10.1016/S1471-4922(02)02350-4
ID - Ginsburg2002
ER -
TY - JOUR
AU - Gulati, S.
PY - 2015
DA - 2015//
TI - Profiling the essential nature of lipid metabolism in asexual blood and gametocyte stages of plasmodium falciparum
JO - Cell Host Microbe
VL - 18
UR - https://doi.org/10.1016/j.chom.2015.08.003
DO - 10.1016/j.chom.2015.08.003
ID - Gulati2015
ER -
TY - JOUR
AU - Olszewski, K. L.
PY - 2009
DA - 2009//
TI - Host-parasite interactions revealed by plasmodium falciparum metabolomics
JO - Cell Host Microbe
VL - 5
UR - https://doi.org/10.1016/j.chom.2009.01.004
DO - 10.1016/j.chom.2009.01.004
ID - Olszewski2009
ER -
TY - STD
TI - Sana TR, et al. Global Mass Spectrometry Based Metabolomics Profiling of Erythrocytes Infected with Plasmodium falciparum. PLoS One. 2013;8(4):e60840.
ID - ref58
ER -
TY - STD
TI - Biddau M, Müller S. Carbon Metabolism of Plasmodium falciparum. Compr Anal Parasite Biol: Metab to Drug Discov. 2016:371.
ID - ref59
ER -
TY - JOUR
AU - Ke, H.
PY - 2015
DA - 2015//
TI - Genetic investigation of tricarboxylic acid metabolism during the plasmodium falciparum life cycle
JO - Cell Rep
VL - 11
UR - https://doi.org/10.1016/j.celrep.2015.03.011
DO - 10.1016/j.celrep.2015.03.011
ID - Ke2015
ER -
TY - STD
TI - MacRae JI, et al. Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite plasmodium falciparum. BMC Biol. 2013;11(1):67.
ID - ref61
ER -
TY - JOUR
AU - Yeh, I.
PY - 2004
DA - 2004//
TI - Computational analysis of plasmodium falciparum metabolism: organizing genomic information to facilitate drug discovery
JO - Genome Res
VL - 14
UR - https://doi.org/10.1101/gr.2050304
DO - 10.1101/gr.2050304
ID - Yeh2004
ER -
TY - JOUR
AU - Liu, J.
PY - 2006
DA - 2006//
TI - Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems
JO - Proc Natl Acad Sci U S A
VL - 103
UR - https://doi.org/10.1073/pnas.0601876103
DO - 10.1073/pnas.0601876103
ID - Liu2006
ER -
TY - JOUR
AU - Krugliak, M.
AU - Zhang, J.
AU - Ginsburg, H.
PY - 2002
DA - 2002//
TI - Intraerythrocytic plasmodium falciparum utilizes only a fraction of the amino acids derived from the digestion of host cell cytosol for the biosynthesis of its proteins
JO - Mol Biochem Parasitol
VL - 119
UR - https://doi.org/10.1016/S0166-6851(01)00427-3
DO - 10.1016/S0166-6851(01)00427-3
ID - Krugliak2002
ER -
TY - JOUR
AU - Asahi, H.
PY - 1996
DA - 1996//
TI - Hypoxanthine: a low molecular weight factor essential for growth of erythrocytic plasmodium falciparum in a serum-free medium
JO - Parasitol
VL - 113
UR - https://doi.org/10.1017/S0031182000066233
DO - 10.1017/S0031182000066233
ID - Asahi1996
ER -
TY - JOUR
AU - Geary, T. G.
PY - 1985
DA - 1985//
TI - Nutritional requirements of plasmodium falciparum in culture. III. Further observations on essential nutrients and antimetabolites
JO - The J Protozool
VL - 32
UR - https://doi.org/10.1111/j.1550-7408.1985.tb03087.x
DO - 10.1111/j.1550-7408.1985.tb03087.x
ID - Geary1985
ER -
TY - JOUR
AU - Miller, L. H.
PY - 2002
DA - 2002//
TI - The pathogenic basis of malaria
JO - Nature
VL - 415
UR - https://doi.org/10.1038/415673a
DO - 10.1038/415673a
ID - Miller2002
ER -
TY - JOUR
AU - Geary, T. G.
AU - Divo, A. A.
AU - Jensen, J. B.
PY - 1985
DA - 1985//
TI - Nutritional requirements of plasmodium falciparum in culture. II. Effects of antimetabolites in a semi defined medium
JO - The J Protozool
VL - 32
UR - https://doi.org/10.1111/j.1550-7408.1985.tb03014.x
DO - 10.1111/j.1550-7408.1985.tb03014.x
ID - Geary1985
ER -
TY - JOUR
AU - Jensen, P. A.
AU - Papin, J. A.
PY - 2011
DA - 2011//
TI - Functional integration of a metabolic network model and expression data without arbitrary thresholding
JO - Bioinform
VL - 27
UR - https://doi.org/10.1093/bioinformatics/btq702
DO - 10.1093/bioinformatics/btq702
ID - Jensen2011
ER -
TY - JOUR
AU - Fang, X.
AU - Reifman, J.
AU - Wallqvist, A.
PY - 2014
DA - 2014//
TI - Modeling metabolism and stage-specific growth of plasmodium falciparum HB3 during the intraerythrocytic developmental cycle
JO - Mol BioSyst
VL - 10
UR - https://doi.org/10.1039/C4MB00115J
DO - 10.1039/C4MB00115J
ID - Fang2014
ER -
TY - JOUR
AU - Chiappino-Pepe, A.
PY - 2017
DA - 2017//
TI - Bioenergetics-based modeling of plasmodium falciparum metabolism reveals its essential genes, nutritional requirements, and thermodynamic bottlenecks
JO - PLoS Comput Biol
VL - 13
UR - https://doi.org/10.1371/journal.pcbi.1005397
DO - 10.1371/journal.pcbi.1005397
ID - Chiappino-Pepe2017
ER -
TY - JOUR
AU - Wallqvist, A.
PY - 2016
DA - 2016//
TI - Metabolic host responses to malarial infection during the intraerythrocytic developmental cycle
JO - BMC Syst Biol
VL - 10
UR - https://doi.org/10.1186/s12918-016-0291-2
DO - 10.1186/s12918-016-0291-2
ID - Wallqvist2016
ER -
TY - JOUR
AU - Tymoshenko, S.
PY - 2013
DA - 2013//
TI - Functional genomics of plasmodium falciparum using metabolic modelling and analysis
JO - Briefings in Functional Genomics
VL - 12
UR - https://doi.org/10.1093/bfgp/elt017
DO - 10.1093/bfgp/elt017
ID - Tymoshenko2013
ER -
TY - STD
TI - Bazzani S, Hoppe A, Holzhütter H-G. Network-based assessment of the selectivity of metabolic drug targets in Plasmodium falciparum with respect to human liver metabolism. BMC Syst Biol. 2012:6(1).
ID - ref74
ER -
TY - STD
TI - Aurrecoechea, C., et al., EuPathDB: the eukaryotic pathogen genomics database resource. Nucleic Acids Res, 2017: 45:D581-D591.
ID - ref75
ER -
TY - JOUR
AU - Gardner, M. J.
PY - 2002
DA - 2002//
TI - Genome sequence of the human malaria parasite plasmodium falciparum
JO - Nat
VL - 419
UR - https://doi.org/10.1038/nature01097
DO - 10.1038/nature01097
ID - Gardner2002
ER -
TY - JOUR
AU - Gajria, B.
PY - 2008
DA - 2008//
TI - ToxoDB: an integrated Toxoplasma gondii database resource
JO - Nucleic Acids Res
VL - 36
ID - Gajria2008
ER -
TY - JOUR
AU - Xia, D.
PY - 2008
DA - 2008//
TI - The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation
JO - Genome Biol
VL - 9
UR - https://doi.org/10.1186/gb-2008-9-7-r116
DO - 10.1186/gb-2008-9-7-r116
ID - Xia2008
ER -
TY - JOUR
AU - Tymoshenko, S.
PY - 2015
DA - 2015//
TI - Metabolic needs and capabilities of Toxoplasma gondii through combined Computational and experimental analysis
JO - PLoS Comput Biol
VL - 11
UR - https://doi.org/10.1371/journal.pcbi.1004261
DO - 10.1371/journal.pcbi.1004261
ID - Tymoshenko2015
ER -
TY - JOUR
AU - Ivens, A. C.
PY - 2005
DA - 2005//
TI - The genome of the Kinetoplastid parasite, Leishmania major
JO - Sci
VL - 309
UR - https://doi.org/10.1126/science.1112680
DO - 10.1126/science.1112680
ID - Ivens2005
ER -
TY - JOUR
AU - Chavali, A. K.
PY - 2008
DA - 2008//
TI - Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major
JO - Mol Syst Biol
VL - 4
ID - Chavali2008
ER -
TY - STD
TI - Orth, J.D., et al., A comprehensive genome-scale reconstruction of Escherichia coli metabolism—2011. Mol Syst Biol, 2011. 7: p. 535–535.
ID - ref82
ER -
TY - JOUR
AU - Heavner, B. D.
AU - Price, N. D.
PY - 2015
DA - 2015//
TI - Comparative analysis of yeast metabolic network models highlights progress, opportunities for metabolic reconstruction
JO - PLoS Comput Biol
VL - 11
UR - https://doi.org/10.1371/journal.pcbi.1004530
DO - 10.1371/journal.pcbi.1004530
ID - Heavner2015
ER -
TY - STD
TI - McConville M. Open questions: microbes, metabolism and host-pathogen interactions. BMC Biol. 2014;12(1):18.
ID - ref84
ER -
TY - JOUR
AU - Wellems, T. E.
AU - Fairhurst, R. M.
PY - 2012
DA - 2012//
TI - An evolving picture of the interactions between malaria parasites and their host erythrocytes
JO - Cell Res
VL - 22
UR - https://doi.org/10.1038/cr.2012.14
DO - 10.1038/cr.2012.14
ID - Wellems2012
ER -
TY - JOUR
AU - Imlay, L.
AU - Odom, A. R.
PY - 2014
DA - 2014//
TI - Isoprenoid metabolism in apicomplexan parasites
JO - Current Clinical Microbiology Reports
VL - 1
UR - https://doi.org/10.1007/s40588-014-0006-7
DO - 10.1007/s40588-014-0006-7
ID - Imlay2014
ER -
TY - JOUR
AU - Mazumdar, J.
AU - Striepen, B.
PY - 2007
DA - 2007//
TI - Make it or take it: fatty acid metabolism of apicomplexan parasites
JO - Eukaryot Cell
VL - 6
UR - https://doi.org/10.1128/EC.00255-07
DO - 10.1128/EC.00255-07
ID - Mazumdar2007
ER -
TY - JOUR
AU - Lanzer, M.
PY - 2006
DA - 2006//
TI - Maurer's clefts: a novel multi-functional organelle in the cytoplasm of plasmodium falciparum-infected erythrocytes
JO - Int J Parasitol
VL - 36
UR - https://doi.org/10.1016/j.ijpara.2005.10.001
DO - 10.1016/j.ijpara.2005.10.001
ID - Lanzer2006
ER -
TY - JOUR
AU - Bannister, L. H.
PY - 2000
DA - 2000//
TI - A brief illustrated guide to the ultrastructure of plasmodium falciparum asexual blood stages
JO - Parasitol Today
VL - 16
UR - https://doi.org/10.1016/S0169-4758(00)01755-5
DO - 10.1016/S0169-4758(00)01755-5
ID - Bannister2000
ER -
TY - JOUR
AU - Baumeister, S.
PY - 2006
DA - 2006//
TI - Evidence for the involvement of plasmodium falciparum proteins in the formation of new permeability pathways in the erythrocyte membrane
JO - Mol Microbiol
VL - 60
UR - https://doi.org/10.1111/j.1365-2958.2006.05112.x
DO - 10.1111/j.1365-2958.2006.05112.x
ID - Baumeister2006
ER -
TY - JOUR
AU - Ginsburg, H.
PY - 1983
DA - 1983//
TI - New permeability pathways induced in membranes of plasmodium falciparum infected erythrocytes
JO - Mol Biochem Parasitol
VL - 8
UR - https://doi.org/10.1016/0166-6851(83)90008-7
DO - 10.1016/0166-6851(83)90008-7
ID - Ginsburg1983
ER -
TY - JOUR
AU - Staines, H. M.
PY - 2006
DA - 2006//
TI - Solute transport via the new permeability pathways in plasmodium falciparum–infected human red blood cells is not consistent with a simple single-channel model
JO - Blood
VL - 108
UR - https://doi.org/10.1182/blood-2006-02-001693
DO - 10.1182/blood-2006-02-001693
ID - Staines2006
ER -
TY - JOUR
AU - Divo, A. A.
PY - 1985
DA - 1985//
TI - Nutritional requirements of plasmodium falciparum in culture. I. Exogenously supplied dialyzable components necessary for continuous growth
JO - J Protozool
VL - 32
UR - https://doi.org/10.1111/j.1550-7408.1985.tb03013.x
DO - 10.1111/j.1550-7408.1985.tb03013.x
ID - Divo1985
ER -
TY - JOUR
AU - Phaiphinit, S.
PY - 2016
DA - 2016//
TI - In silico multiple-targets identification for heme detoxification in the human malaria parasite plasmodium falciparum
JO - Infect Genet Evol
VL - 37
UR - https://doi.org/10.1016/j.meegid.2015.11.025
DO - 10.1016/j.meegid.2015.11.025
ID - Phaiphinit2016
ER -
TY - JOUR
AU - Ghorbal, M.
PY - 2014
DA - 2014//
TI - Genome editing in the human malaria parasite plasmodium falciparum using the CRISPR-Cas9 system
JO - Nat Biotech
VL - 32
UR - https://doi.org/10.1038/nbt.2925
DO - 10.1038/nbt.2925
ID - Ghorbal2014
ER -
TY - JOUR
AU - Lee, M. C. S.
AU - Fidock, D. A.
PY - 2014
DA - 2014//
TI - CRISPR-mediated genome editing of plasmodium falciparum malaria parasites
JO - Genome Med
VL - 6
UR - https://doi.org/10.1186/s13073-014-0063-9
DO - 10.1186/s13073-014-0063-9
ID - Lee2014
ER -
TY - JOUR
AU - Wagner, J. C.
PY - 2014
DA - 2014//
TI - Efficient CRISPR-Cas9-mediated genome editing in plasmodium falciparum
JO - Nat Meth
VL - 11
UR - https://doi.org/10.1038/nmeth.3063
DO - 10.1038/nmeth.3063
ID - Wagner2014
ER -
TY - JOUR
AU - Lu, J.
PY - 2016
DA - 2016//
TI - A redesigned CRISPR/Cas9 system for marker-free genome editing in plasmodium falciparum
JO - Parasit Vectors
VL - 9
UR - https://doi.org/10.1186/s13071-015-1291-6
DO - 10.1186/s13071-015-1291-6
ID - Lu2016
ER -
TY - JOUR
AU - Ramya, T. N. C.
PY - 2007
DA - 2007//
TI - Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in plasmodium falciparum
JO - Antimicrob Agents Chemother
VL - 51
UR - https://doi.org/10.1128/AAC.00808-06
DO - 10.1128/AAC.00808-06
ID - Ramya2007
ER -
TY - JOUR
AU - Ke, H.
PY - 2014
DA - 2014//
TI - The heme biosynthesis pathway is essential for plasmodium falciparum development in mosquito stage but not in blood stages
JO - J Biol Chem
VL - 289
UR - https://doi.org/10.1074/jbc.M114.615831
DO - 10.1074/jbc.M114.615831
ID - Ke2014
ER -
TY - JOUR
AU - Nagaraj, V. A.
PY - 2013
DA - 2013//
TI - Malaria parasite-synthesized Heme is essential in the mosquito and liver stages and complements host Heme in the blood stages of infection
JO - PLoS Pathog
VL - 9
UR - https://doi.org/10.1371/journal.ppat.1003522
DO - 10.1371/journal.ppat.1003522
ID - Nagaraj2013
ER -
TY - JOUR
AU - Ho, M. -. C.
PY - 2009
DA - 2009//
TI - Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases
JO - Biochemistry
VL - 48
UR - https://doi.org/10.1021/bi9012484
DO - 10.1021/bi9012484
ID - Ho2009
ER -
TY - JOUR
AU - Zhou, Y.
AU - Li, W.
AU - Xiao, Y.
PY - 2016
DA - 2016//
TI - Profiling of multiple targets of artemisinin activated by hemin in cancer cell proteome
JO - ACS Chem Biol
VL - 11
UR - https://doi.org/10.1021/acschembio.5b01043
DO - 10.1021/acschembio.5b01043
ID - Zhou2016
ER -
TY - JOUR
AU - Ismail, H. M.
PY - 2016
DA - 2016//
TI - Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites plasmodium falciparum 3D7
JO - Proc Natl Acad Sci
VL - 113
UR - https://doi.org/10.1073/pnas.1600459113
DO - 10.1073/pnas.1600459113
ID - Ismail2016
ER -
TY - STD
TI - Prieto JH, et al. Large-Scale Differential Proteome Analysis in Plasmodium falciparum under Drug Treatment. PLoS One. 2008;3(12):e4098.
ID - ref105
ER -
TY - JOUR
AU - Creek, D. J.
PY - 2016
DA - 2016//
TI - Metabolomics-based screening of the malaria box reveals both novel and established mechanisms of action
JO - Antimicrob Agents Chemother
VL - 60
UR - https://doi.org/10.1128/AAC.01226-16
DO - 10.1128/AAC.01226-16
ID - Creek2016
ER -
TY - JOUR
AU - Pretzel, J.
PY - 2016
DA - 2016//
TI - Characterization and redox regulation of plasmodium falciparum methionine adenosyltransferase
JO - J Biochem
VL - 160
UR - https://doi.org/10.1093/jb/mvw045
DO - 10.1093/jb/mvw045
ID - Pretzel2016
ER -
TY - JOUR
AU - Salcedo-Sora, J. E.
PY - 2011
DA - 2011//
TI - The molecular basis of folate salvage in plasmodium falciparum characterization of two folate transporters
JO - J Biol Chem
VL - 286
UR - https://doi.org/10.1074/jbc.M111.286054
DO - 10.1074/jbc.M111.286054
ID - Salcedo-Sora2011
ER -
TY - JOUR
AU - Wishart, D. S.
PY - 2007
DA - 2007//
TI - HMDB: the human metabolome database
JO - Nucleic Acids Res
VL - 35
UR - https://doi.org/10.1093/nar/gkl923
DO - 10.1093/nar/gkl923
ID - Wishart2007
ER -
TY - JOUR
AU - Wang, J.
PY - 2015
DA - 2015//
TI - Haem-activated promiscuous targeting of artemisinin in plasmodium falciparum
JO - Nat Commun
VL - 6
UR - https://doi.org/10.1038/ncomms10111
DO - 10.1038/ncomms10111
ID - Wang2015
ER -
TY - JOUR
AU - Singh, S.
PY - 1997
DA - 1997//
TI - Characterization of Simian malarial parasite (plasmodium knowlesi)-induced putrescine transport in rhesus monkey erythrocytes a NOVEL PUTRESCINE CONJUGATE ARRESTS IN VITRO GROWTH OF SIMIAN MALARIAL PARASITE (PLASMODIUM KNOWLESI) AND CURES MULTIDRUG RESISTANT MURINE MALARIA (Plasmodium YOELII) INFECTION IN VIVO
JO - J Biol Chem
VL - 272
UR - https://doi.org/10.1074/jbc.272.21.13506
DO - 10.1074/jbc.272.21.13506
ID - Singh1997
ER -
TY - JOUR
AU - Assaraf, Y. G.
PY - 1987
DA - 1987//
TI - Effect of polyamine depletion on macromolecular synthesis of the malarial parasite, plasmodium falciparum, cultured in human erythrocytes
JO - Biochem J
VL - 242
UR - https://doi.org/10.1042/bj2420221
DO - 10.1042/bj2420221
ID - Assaraf1987
ER -
TY - JOUR
AU - Stevens, L.
PY - 1970
DA - 1970//
TI - The biochemical role of naturally occurring polyamines in nucleic acid synthesis
JO - Biol Rev
VL - 45
UR - https://doi.org/10.1111/j.1469-185X.1970.tb01073.x
DO - 10.1111/j.1469-185X.1970.tb01073.x
ID - Stevens1970
ER -
TY - JOUR
AU - Mandal, S.
PY - 2013
DA - 2013//
TI - Depletion of cellular polyamines, spermidine and spermine, causes a total arrest in translation and growth in mammalian cells
JO - Proc Natl Acad Sci
VL - 110
UR - https://doi.org/10.1073/pnas.1219002110
DO - 10.1073/pnas.1219002110
ID - Mandal2013
ER -
TY - JOUR
AU - Teuscher, F.
PY - 2012
DA - 2012//
TI - Phenotypic changes in artemisinin-resistant plasmodium falciparum lines in vitro: evidence for decreased sensitivity to dormancy and growth inhibition
JO - Antimicrob Agents Chemother
VL - 56
UR - https://doi.org/10.1128/AAC.05456-11
DO - 10.1128/AAC.05456-11
ID - Teuscher2012
ER -
TY - JOUR
AU - Srivastava, A.
PY - 2016
DA - 2016//
TI - Stage-specific changes in plasmodium metabolism required for differentiation and adaptation to different host and vector environments
JO - PLoS Pathog
VL - 12
UR - https://doi.org/10.1371/journal.ppat.1006094
DO - 10.1371/journal.ppat.1006094
ID - Srivastava2016
ER -
TY - JOUR
AU - Müller, S.
AU - Kappes, B.
PY - 2007
DA - 2007//
TI - Vitamin and cofactor biosynthesis pathways in plasmodium and other apicomplexan parasites
JO - Trends Parasitol
VL - 23
UR - https://doi.org/10.1016/j.pt.2007.01.009
DO - 10.1016/j.pt.2007.01.009
ID - Müller2007
ER -
TY - JOUR
AU - Maenpuen, S.
PY - 2009
DA - 2009//
TI - Characterization of plasmodium falciparum serine hydroxymethyltransferase—a potential antimalarial target
JO - Mol Biochem Parasitol
VL - 168
UR - https://doi.org/10.1016/j.molbiopara.2009.06.010
DO - 10.1016/j.molbiopara.2009.06.010
ID - Maenpuen2009
ER -
TY - JOUR
AU - Salcedo, E.
AU - Sims, P. F. G.
AU - Hyde, J. E.
PY - 2005
DA - 2005//
TI - A glycine-cleavage complex as part of the folate one-carbon metabolism of plasmodium falciparum
JO - Trends Parasitol
VL - 21
UR - https://doi.org/10.1016/j.pt.2005.07.001
DO - 10.1016/j.pt.2005.07.001
ID - Salcedo2005
ER -
TY - JOUR
AU - Pornthanakasem, W.
PY - 2012
DA - 2012//
TI - Plasmodium serine hydroxymethyltransferase: indispensability and display of distinct localization
JO - Malar J
VL - 11
UR - https://doi.org/10.1186/1475-2875-11-387
DO - 10.1186/1475-2875-11-387
ID - Pornthanakasem2012
ER -
TY - JOUR
AU - França, T. C. C.
AU - Pascutti, P. G.
AU - Ramalho, T. C.
PY - 2005
DA - 2005//
TI - A three-dimensional structure of plasmodium falciparum serine hydroxymethyltransferase in complex with glycine and 5-formyl-tetrahydrofolate. Homology modeling and molecular dynamics
JO - Biophys Chem
VL - 115
UR - https://doi.org/10.1016/j.bpc.2004.12.002
DO - 10.1016/j.bpc.2004.12.002
ID - França2005
ER -
TY - JOUR
AU - Schulz, J. B.
PY - 2000
DA - 2000//
TI - Glutathione, oxidative stress and neurodegeneration
JO - Eur J Biochem
VL - 267
UR - https://doi.org/10.1046/j.1432-1327.2000.01595.x
DO - 10.1046/j.1432-1327.2000.01595.x
ID - Schulz2000
ER -
TY - JOUR
AU - Mittler, R.
PY - 2002
DA - 2002//
TI - Oxidative stress, antioxidants and stress tolerance
JO - Trends Plant Sci
VL - 7
UR - https://doi.org/10.1016/S1360-1385(02)02312-9
DO - 10.1016/S1360-1385(02)02312-9
ID - Mittler2002
ER -
TY - JOUR
AU - Becker, K.
PY - 2004
DA - 2004//
TI - Oxidative stress in malaria parasite-infected erythrocytes: host–parasite interactions
JO - Int J Parasitol
VL - 34
UR - https://doi.org/10.1016/j.ijpara.2003.09.011
DO - 10.1016/j.ijpara.2003.09.011
ID - Becker2004
ER -
TY - JOUR
AU - Färber, P. M.
PY - 1996
DA - 1996//
TI - Molecular cloning and characterization of a putative glutathione reductase gene, the PfGR2 gene, from plasmodium falciparum
JO - Eur J Biochem
VL - 239
UR - https://doi.org/10.1111/j.1432-1033.1996.0655u.x
DO - 10.1111/j.1432-1033.1996.0655u.x
ID - Färber1996
ER -
TY - JOUR
AU - Kehr, S.
PY - 2010
DA - 2010//
TI - Compartmentation of redox metabolism in malaria parasites
JO - PLoS Pathog
VL - 6
UR - https://doi.org/10.1371/journal.ppat.1001242
DO - 10.1371/journal.ppat.1001242
ID - Kehr2010
ER -
TY - STD
TI - Ritchie, M.E., et al., Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res, 2015. 43(7): p. e47-e47.
ID - ref127
ER -
TY - STD
TI - White LJ, et al. Defining the In Vivo Phenotype of Artemisinin-Resistant Falciparum Malaria: A Modelling Approach. PLoS Med. 2015;12(4):e1001823.
ID - ref128
ER -
TY - JOUR
AU - Liaw, A.
AU - Wiener, M.
PY - 2002
DA - 2002//
TI - Classification and regression by randomForest
JO - R News
VL - 2
ID - Liaw2002
ER -
TY - STD
TI - Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc. Series B (Methodological). 1995:289–300.
ID - ref130
ER -
TY - STD
TI - Benjamini Y, Yekutieli D. The control of the false discovery rate in multiple testing under dependency. Ann Stat. 2001:1165–88.
ID - ref131
ER -
TY - STD
TI - Becker SA, et al. Quantitative prediction of cellular metabolism with constraint-based models: the COBRA toolbox. Nat Protoc. 2007;2
ID - ref132
ER -
TY - JOUR
AU - Orth, J. D.
AU - Thiele, I.
AU - Palsson, B. O.
PY - 2010
DA - 2010//
TI - What is flux balance analysis?
JO - Nat Biotech
VL - 28
UR - https://doi.org/10.1038/nbt.1614
DO - 10.1038/nbt.1614
ID - Orth2010
ER -
TY - STD
TI - Oberhardt MA, et al. Metabolic network analysis of Pseudomonas Aeruginosa during chronic cystic fibrosis lung infection. J Bacteriol. 2010;192
ID - ref134
ER -
TY - JOUR
AU - Gudmundsson, S.
AU - Thiele, I.
PY - 2010
DA - 2010//
TI - Computationally efficient flux variability analysis
JO - BMC Bioinform
VL - 11
UR - https://doi.org/10.1186/1471-2105-11-489
DO - 10.1186/1471-2105-11-489
ID - Gudmundsson2010
ER -
TY - JOUR
AU - Kanehisa, M.
PY - 2016
DA - 2016//
TI - KEGG as a reference resource for gene and protein annotation
JO - Nucleic Acids Res
VL - 44
UR - https://doi.org/10.1093/nar/gkv1070
DO - 10.1093/nar/gkv1070
ID - Kanehisa2016
ER -
TY - JOUR
AU - Gasteiger, E.
PY - 2003
DA - 2003//
TI - ExPASy: the proteomics server for in-depth protein knowledge and analysis
JO - Nucleic Acids Res
VL - 31
UR - https://doi.org/10.1093/nar/gkg563
DO - 10.1093/nar/gkg563
ID - Gasteiger2003
ER -
TY - JOUR
AU - Ginsburg, H.
PY - 2006
DA - 2006//
TI - Progress in in silico functional genomics: the malaria metabolic pathways database
JO - Trends Parasitol
VL - 22
UR - https://doi.org/10.1016/j.pt.2006.04.008
DO - 10.1016/j.pt.2006.04.008
ID - Ginsburg2006
ER -
TY - STD
TI - Yeh E, DeRisi JL. Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum. PLoS Biol. 2011;9(8):e1001138.
ID - ref139
ER -
TY - JOUR
AU - Woodrow, C. J.
AU - Burchmore, R. J.
AU - Krishna, S.
PY - 2000
DA - 2000//
TI - Hexose permeation pathways in plasmodium falciparum-infected erythrocytes
JO - Proc Natl Acad Sci U S A
VL - 97
UR - https://doi.org/10.1073/pnas.170153097
DO - 10.1073/pnas.170153097
ID - Woodrow2000
ER -
TY - JOUR
AU - Anfinsen, C. B.
PY - 1946
DA - 1946//
TI - STUDIES ON MALARIAL PARASITES : VIII. FACTORS AFFECTING THE GROWTH OF PLASMODIUM KNOWLESI IN VITRO
JO - J Exp Med
VL - 84
UR - https://doi.org/10.1084/jem.84.6.607
DO - 10.1084/jem.84.6.607
ID - Anfinsen1946
ER -
TY - JOUR
AU - Jiang, L.
PY - 2000
DA - 2000//
TI - Potent and selective activity of a combination of thymidine and 1843U89, a folate-based thymidylate synthase inhibitor, against plasmodium falciparum
JO - Antimicrob Agents Chemother
VL - 44
UR - https://doi.org/10.1128/AAC.44.4.1047-1050.2000
DO - 10.1128/AAC.44.4.1047-1050.2000
ID - Jiang2000
ER -
TY - JOUR
AU - Yu, M.
PY - 2008
DA - 2008//
TI - The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites
JO - Cell Host Microbe
VL - 4
UR - https://doi.org/10.1016/j.chom.2008.11.001
DO - 10.1016/j.chom.2008.11.001
ID - Yu2008
ER -
TY - JOUR
AU - Vaughan, A. M.
PY - 2009
DA - 2009//
TI - Type II fatty acid synthesis is essential only for malaria parasite late liver stage development
JO - Cell Microbiol
VL - 11
UR - https://doi.org/10.1111/j.1462-5822.2008.01270.x
DO - 10.1111/j.1462-5822.2008.01270.x
ID - Vaughan2009
ER -
TY - JOUR
AU - Deng, X.
PY - 2009
DA - 2009//
TI - Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds
JO - J Biol Chem
VL - 284
UR - https://doi.org/10.1074/jbc.M109.028589
DO - 10.1074/jbc.M109.028589
ID - Deng2009
ER -
TY - JOUR
AU - McRobert, L.
AU - McConkey, G. A.
PY - 2002
DA - 2002//
TI - RNA interference (RNAi) inhibits growth of plasmodium falciparum
JO - Mol Biochem Parasitol
VL - 119
UR - https://doi.org/10.1016/S0166-6851(01)00429-7
DO - 10.1016/S0166-6851(01)00429-7
ID - McRobert2002
ER -
TY - STD
TI - Nguyen, C., et al., Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. (0022–2623 (Print)).
ID - ref147
ER -
TY - STD
TI - Thornalley, P.J., R.J. Strath M Fau - Wilson, and R.J. Wilson, Antimalarial activity in vitro of the glyoxalase I inhibitor diester, S-p-bromobenzylglutathione diethyl ester. (0006–2952 (Print)).
ID - ref148
ER -
TY - JOUR
AU - Hanada, K.
PY - 2002
DA - 2002//
TI - Plasmodium falciparum phospholipase C hydrolyzing sphingomyelin and lysocholinephospholipids is a possible target for malaria chemotherapy
JO - J Exp Med
VL - 195
UR - https://doi.org/10.1084/jem.20010724
DO - 10.1084/jem.20010724
ID - Hanada2002
ER -
TY - STD
TI - Silva, A.M., et al., Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum. (0027–8424 (Print)).
ID - ref150
ER -
TY - JOUR
AU - Hoepfner, D.
PY - 2012
DA - 2012//
TI - Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin
JO - Cell Host Microbe
VL - 11
UR - https://doi.org/10.1016/j.chom.2012.04.015
DO - 10.1016/j.chom.2012.04.015
ID - Hoepfner2012
ER -
TY - JOUR
AU - Patzewitz, E. M.
AU - Wong, E. H.
AU - Muller, S.
PY - 2012
DA - 2012//
TI - Dissecting the role of glutathione biosynthesis in plasmodium falciparum
JO - Mol Microbiol
VL - 83
UR - https://doi.org/10.1111/j.1365-2958.2011.07933.x
DO - 10.1111/j.1365-2958.2011.07933.x
ID - Patzewitz2012
ER -
TY - JOUR
AU - Sturm, N.
PY - 2009
DA - 2009//
TI - Identification of proteins targeted by the thioredoxin superfamily in plasmodium falciparum
JO - PLoS Pathog
VL - 5
UR - https://doi.org/10.1371/journal.ppat.1000383
DO - 10.1371/journal.ppat.1000383
ID - Sturm2009
ER -
TY - JOUR
AU - Belorgey, D.
AU - Lanfranchi, D. A.
AU - Davioud-Charvet, E.
PY - 2013
DA - 2013//
TI - 1,4-naphthoquinones and other NADPH-dependent glutathione reductase-catalyzed redox cyclers as antimalarial agents
JO - Curr Pharm Des
VL - 19
UR - https://doi.org/10.2174/1381612811319140003
DO - 10.2174/1381612811319140003
ID - Belorgey2013
ER -
TY - JOUR
AU - Muller, S.
PY - 2015
DA - 2015//
TI - Role and regulation of glutathione metabolism in plasmodium falciparum
JO - Mol
VL - 20
UR - https://doi.org/10.3390/molecules200610511
DO - 10.3390/molecules200610511
ID - Muller2015
ER -
TY - JOUR
AU - Pastrana-Mena, R.
PY - 2010
DA - 2010//
TI - Glutathione reductase-null malaria parasites have normal blood stage growth but arrest during development in the mosquito
JO - J Biol Chem
VL - 285
UR - https://doi.org/10.1074/jbc.M110.122275
DO - 10.1074/jbc.M110.122275
ID - Pastrana-Mena2010
ER -