Fig. 2
From: eDGAR: a database of Disease-Gene Associations with annotated Relationships among genes
Distribution of best IC values of GO terms for genes involved in multigenic diseases. a GO terms shared by genes; b GO terms after enrichment with NET-GE. For each multigenic disease, IC values of gene-associated GO terms (of the three different roots) are evaluated (Eq. 1). In the figure, the highest IC for each disease is shown. The frequency is computed with respect to the total number of multigenic diseases (621). When ICÂ =Â 0, genes associated with multigenic disease do not share or enrich GO terms (panel a and b respectively)