Table 4 Summary of effects of mutations predicted by the automated methods
| Â | rBAT | b(0+)AT |
|---|---|---|
SIFT – Tolerated | 23 | 11 |
SIFT – Damaging | 70 | 48 |
PolyPhen2 (HumVar) – benign | 12 | 14 |
PolyPhen2 (HumVar) – possibly damaging | 15 | 16 |
PolyPhen2 (HumVar) – probably damaging | 66 | 29 |
PolyPhen2 (HumDiv) – benign | 8 | 15 |
PolyPhen2 (HumDiv) – possibly damaging | 11 | 4 |
PolyPhen2 (HumDiv) – probably damaging | 74 | 40 |
MutationAssessor – neutral | 2 | 4 |
MutationAssessor – low | 17 | 6 |
MutationAssessor – medium | 40 | 29 |
MutationAssessor - high | 34 | 20 |
FATHMM – Neutral | 0 | 0 |
FATHMM – Damaging | 93 | 59 |
Condel - Neutral | 1 | 7 |
Condel – Damaging | 92 | 52 |
CADD- Neutral | 5 | 6 |
CADD - Deleterious | 88 | 53 |