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Fig. 5 | BMC Genomics

Fig. 5

From: Short DNA sequence patterns accurately identify broadly active human enhancers

Fig. 5

Binding motifs for broadly expressed TFs are more GC- and CpG-rich than motifs for context-specific TFs. The mean (a) GC content and (b) CpG content of motifs recognized by 313 broadly expressed TFs (blue) was significantly greater than that of 250 context-specific TFs (green). For TFs with multiple motifs, we took the mean over motifs. Box plots show median, and 1st/3rd quartile. P-values were calculated using the Wilcoxon Rank Sum test

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