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Fig. 2 | BMC Genomics

Fig. 2

From: The MalR type regulator AcrC is a transcriptional repressor of acarbose biosynthetic genes in Actinoplanes sp. SE50/110

Fig. 2

Differential transcriptional analysis of the deletion mutant ΔacrC compared to the wild type. a Ratio/intensity plot from whole genome microarrays of the strain Actinoplanes sp. SE50/110 ΔacrC compared to the Actinoplanes sp. SE50/110 wild type grown in maltose minimal medium (Mal-MM). Green and red dots represent genes with significantly different transcript levels in the ΔacrC strain. Filled dots show acb genes. b Ratio/intensity plot from whole genome microarrays of the strain ΔacrC compared to the wild type grown in glucose minimal medium (Glc-MM). c Heatmap of the fold change of transcript abundance for the genes of the acb gene cluster, derived from the microarray data shown in 2A and 2B. Significance of p < 0.05 is marked with a single asterisk, significance of p < 0.01 with two asterisks (t-test, two-sample, Holm). d Transcriptional organization of the acb gene cluster with protein localizations depicted by coloring

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