Fig. 5
From: PiiL: visualization of DNA methylation and gene expression data in gene pathways
Effect of selecting different subsets of CpG sites in the “TNF signaling pathway”. Genes colored in gray do not contain any passing CpG sites. Filtering criteria are: (a) all CpG sites; (b) sites located at upstream or in the UTR5 of a gene; (c) sites with a standard deviation >0.2; (d) sites identified by Saguaro; (e) Gene expression; (f) sites with a high inverse correlation between methylation and expression. For each gene, the three boxes are colored according to average methylation (a-d and f) or median expression (e)