Table 1 Predicted secondary metabolite loci in Z. tritici
Cluster number | Secondary metabolite class | Predicted key biosynthetic gene(s) | Predicted transporter | Resident transcription factor | Subtelomeric | Evidence of transcriptional co-expression? | AntiSMASH | SMURF | ||
|---|---|---|---|---|---|---|---|---|---|---|
Cluster boundary | No. of genes | Cluster boundary | No. of genes | |||||||
1 | NRPS-Like | Mycgr3G107072 | YES | NO | NO | NO | 1:2,172,553:2,212,738 | 12 | 1:2,189,682:2,216,244 | 8 |
2 | Transporter | Na | YES | NO | NO | NO | 1:2,306,586:2,310,597 | 2 | Na | Na |
3 | Terpene | Mycgr3G34236 | NO | NO | NO | YES | 1:2,366,583:2,438,578 | 28 | Na | Na |
4 | Terpene | Mycgr3G33174 | YES | NO | NO | NO | 1:3,518,416:3,535,837 | 9 | Na | Na |
5 | PKS | Mycgr3G83965 | NO | NO | NO | NO | 1:3,821,874:3,860,702 | 14 | Na | Na |
6 | NRPS | Mycgr3G16590 | YES | YES | NO | NO | 1:5,128,643:5,192,491 | 23 | Na | Na |
7 | PKS | Mycgr3G67477 | YES | YES | NO | YES | 1:5,513,274:5,566,181 | 17 | 1:5,524,934:5,578,932 | 20 |
8 | PKS | Mycgr3G9788 | YES | YES | YES | YES | 2:31,258:149,728 | 37 | 2:123,001:157,676 | 11 |
9 | NRPS | Mycgr3G19958 | NO | NO | YES | NO | 2:222,377:310,014 | 19 | 2:260,654:284,183 | 5 |
10 | NRPS | Mycgr3G36951 | YES | NO | NO | NO | 2:420,337:471,819 | 14 | 2:433,742:453,243 | 2 |
11 | NRPS | Mycgr3G90558 | YES | NO | NO | NO | 2:1,008,626:1,058,615 | 13 | 2:1,026,842:1,052,480 | 6 |
12 | Terpene | Mycgr3G99148 | NO | YES | NO | YES | 2:1,934,751:2,046,004 | 31 | Na | Na |
13 | PKS-Like | Mycgr3G39149 | YES | NO | YES | YES | Na | Na | 3:3,181,477:3,213,160 | 13 |
14 | NRPS | Mycgr3G39931, Mycgr3G40534 | YES | NO | YES | NO | 4:12,877:43,949 | 7 | Na | Na |
15 | PKS | Mycgr3G100089 | YES | YES | YES | YES | 5:85,463:149,465 | 22 | 5:94,206:129,292 | 12 |
16 | NRPS-Like | Mycgr3G93235, Mycgr3G100227 | NO | YES | NO | YES | 5:1,291,545:1,380,182 | 31 | 5:1,309,417:1,324,422 | 4 |
17 | PKS | Mycgr3G72709 | YES | YES | YES | YES | 6:72,339:170,251 | 36 | 6:106,974:121,853 | 4 |
18 | NRPS | Mycgr3G72768 | YES | NO | YES | YES | 6:283,399:352,537 | 24 | 6:310,922:346,260 | 11 |
19 | NRPS | Mycgr3G44313 | NO | NO | NO | YES | 6:1,808,394:1,845,239 | 16 | 6:1,821,703:1,841,259 | 9 |
20 | NRPS | Mycgr3G109989 | YES | YES | NO | NO | 6:2,243,873:2,278,779 | 9 | Na | Na |
21 | PKS | Mycgr3G45348 | YES | NO | YES | NO | 7:2,566,479:2,608,068 | 12 | 7:2,577,096:2,606,813 | 8 |
22 | NRPS | Mycgr3G110642 | YES | NO | YES | NO | 8:2,346,378:2,374,211 | 8 | 8:2,352,913:2,362,665 | 2 |
23 | NRPS-Like | Mycgr3G75370 | YES | YES | NO | YES | 9:483,924:714,190 | 65 | Na | Na |
24 | PKS | Mycgr3G47832 | YES | YES | NO | NO | 9:1,474,679:1,516,611 | 12 | 9:1,494,054:1,506,383 | 3 |
25 | Terpene | Mycgr3G76129 | YES | YES | NO | NO | 10:341,276:419,193 | 29 | Na | Na |
26 | Hybrid PKS- NRPS | Mycgr3G62978 | YES | NO | NO | YES | 10:425,702:485,734 | 20 | 10:439,622:460,865 | 6 |
27 | PKS | Mycgr3G101493 | YES | NO | YES | YES | 10:1,274,562:1,480,511 | 54 | 10:1,436,111:1,437,155 | 7 |
28 | NRPS-Like | Mycgr3G49555 | NO | NO | NO | YES | 11:393,046:429,601 | 12 | 11:409,058:423,584 | 5 |
29 | PKS | Mycgr3G96592 | NO | YES | NO | NO | 11:566,694:611,143 | 14 | Na | Na |
30 | NRPS-Like | Mycgr3G50095 | YES | YES | NO | NO | 11:823,532:917,882 | 30 | 11:849,800:868,675 | 7 |
31 | NRPS | Mycgr3G96900 | YES | NO | YES | YES | 12:157,368:195,467 | 15 | Na | Na |
32 | NRPS-Like | Mycgr3G77312 | NO | NO | NO | NO | 12:434,096:471,899 | 9 | Na | Na |
33 | PKS | Mycgr3G51018 | NO | NO | NO | YES | 13:656,107:712,077 | 17 | Na | Na |
34 | Terpene | Mycgr3G101921, Mycgr3G12838 | YES | NO | YES | NO | 13:1,116,277:1,139,970 | 8 | Na | Na |