Fig. 4

Differential expression of genes located in the candidate regions for mastitis resistance post treatment with LPS. Each column represents gene expression level in sheep bone marrow-derived macrophages 0, 2, 4, 7 and 24 h post treatment with LPS, respectively. Expression level is shown as (a) average TPM (transcripts per million) at the 5 different time points, and (b) as log₂ fold change in expression at 2, 4, 7 and 24 h relative to expression at 0 h. Significance thresholds indicated as: P < 0.05*, P < 0.01** and P < 0.001***